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    Taf5 TBP-associated factor 5 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 47900, updated on 9-Dec-2024

    Summary

    Official Symbol
    Taf5provided by FlyBase
    Official Full Name
    TBP-associated factor 5provided by FlyBase
    Primary source
    FLYBASE:FBgn0010356
    Locus tag
    Dmel_CG7704
    See related
    AllianceGenome:FB:FBgn0010356
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG7704; d80; Dmel\CG7704; dmTaf5; dmTAF5; dTAF5; dTAFii80; dTAFII85; dTAF[[II]]80; p85; TAF; taf5; TAF5; Taf80; TAF80; TAF80/85; Taf85; TAFII80; TAFII85; TAF[II]80; TAF[[II]]; Taf[[II]]80; TAF[[II]]80; TAF[[II]]80/85; TAF[[II]]85; TFIID; TFIID 85
    Summary
    Contributes to RNA polymerase II general transcription initiation factor activity. Involved in transcription initiation at RNA polymerase II promoter. Located in nucleus. Part of transcription factor TFIID complex. Is expressed in male accessory gland; organism; seminal vesicle; and testis. Orthologous to human TAF5 (TATA-box binding protein associated factor 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Taf5 in Genome Data Viewer
    Location:
    47C5-47C5; 2-63 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (10877312..10879673, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (6764817..6767178, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene no child left behind Neighboring gene Peroxin 6 Neighboring gene Hydroxyacid oxidase

    Genomic regions, transcripts, and products

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    TBP-associated factor 5
    Names
    CG7704-PA
    TBP associated factor 80
    TBP-associated factor
    TBP-associated factor 80
    TBP-associated factor 80kD
    Taf5-PA

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      10877312..10879673 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_057609.6NP_476957.1  TBP-associated factor 5 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_476957.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P49846, Q9V5R1
      Related
      FBpp0087335
      Conserved Domains (4) summary
      cd08044
      Location:114245
      TAF5_NTD2; TAF5_NTD2 is the second conserved N-terminal region of TATA Binding Protein (TBP) Associated Factor 5 (TAF5), involved in forming Transcription Factor IID (TFIID)
      COG2319
      Location:319674
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:373646
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:380448
      7WD40; WD40 repeat [structural motif]