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    Hr83 Hormone receptor 83 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 40783, updated on 17-Dec-2024

    Summary

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    Official Symbol
    Hr83provided by FlyBase
    Official Full Name
    Hormone receptor 83provided by FlyBase
    Primary source
    FLYBASE:FBgn0037436
    Locus tag
    Dmel_CG10296
    See related
    AllianceGenome:FB:FBgn0037436
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10296; DHR83; Dmel\CG10296; HR83; NR2E5
    Summary
    Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Located in heterochromatin and nucleolus. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Hr83 in Genome Data Viewer
    Location:
    83E4-83E4; 3-47.5 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (6349243..6350512)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (2174965..2176234)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Small ribonucleoprotein particle protein SmD2 Neighboring gene uncharacterized protein Neighboring gene p21-activated kinase Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. DHR51, the Drosophila melanogaster homologue of the human photoreceptor cell-specific nuclear receptor, is a thiolate heme-binding protein. de Rosny E, et al. Biochemistry, 2008 Dec 16. PMID 19086271
    2. Dynamic regulation of Drosophila nuclear receptor activity in vivo. Palanker L, et al. Development, 2006 Sep. PMID 16914501, Free PMC Article
    3. Spatial profiling of nuclear receptor transcription patterns over the course of Drosophila development. Wilk R, et al. G3 (Bethesda), 2013 Jul 8. PMID 23665880, Free PMC Article
    4. The Drosophila FTZ-F1 nuclear receptor mediates juvenile hormone activation of E75A gene expression through an intracellular pathway. Dubrovsky EB, et al. J Biol Chem, 2011 Sep 23. PMID 21832074, Free PMC Article
    5. Comparison of complete nuclear receptor sets from the human, Caenorhabditis elegans and Drosophila genomes. Maglich JM, et al. Genome Biol, 2001. PMID 11532213, Free PMC Article

    See all (35) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nuclear receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables nuclear receptor activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in heterochromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    hormone receptor 83
    Names
    CG10296-PA
    Hr83-PA
    drosophila hormone receptor 83

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      6349243..6350512
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_141390.1 → NP_649647.1  hormone receptor 83 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_649647.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VI12
      Related
      FBpp0081210, FBtr0081713
      Conserved Domains (1) summary
      cd06957
      Location:7 → 88
      NR_DBD_PNR_like_2; DNA-binding domain of the photoreceptor cell-specific nuclear receptor (PNR) like is composed of two C4-type zinc fingers
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VI12 Q9VI12

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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