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    SP1173 SP1173 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38744, updated on 9-Dec-2024

    Summary

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    Official Symbol
    SP1173provided by FlyBase
    Official Full Name
    SP1173provided by FlyBase
    Primary source
    FLYBASE:FBgn0035710
    Locus tag
    Dmel_CG10121
    See related
    AllianceGenome:FB:FBgn0035710
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG10121; Dmel\CG10121
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be active in membrane. Is expressed in several structures, including adult head; central brain primordium; embryonic stomatogastric nervous system; ganglia; and larval muscle cell. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See SP1173 in Genome Data Viewer
    Location:
    65C1-65C3; 3-17 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (6689327..6703521, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (6682427..6696621, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45173 Neighboring gene Gustatory receptor-like 65a Neighboring gene uncharacterized protein Neighboring gene pale

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Hox proteins Ubx and AbdA collaborate with the transcription pausing factor M1BP to regulate gene transcription. Zouaz A, et al. EMBO J, 2017 Oct 2. PMID 28871058, Free PMC Article
    2. dTcf/Pangolin suppresses growth and tumor formation in Drosophila. Song S, et al. Proc Natl Acad Sci U S A, 2019 Jul 9. PMID 31235567, Free PMC Article
    3. Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Hollien J, et al. Science, 2006 Jul 7. PMID 16825573
    4. Automatic image analysis for gene expression patterns of fly embryos. Peng H, et al. BMC Cell Biol, 2007 Jul 10. PMID 17634097, Free PMC Article
    5. Male-specific fruitless isoforms target neurodevelopmental genes to specify a sexually dimorphic nervous system. Neville MC, et al. Curr Biol, 2014 Feb 3. PMID 24440396, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables transmembrane transporter activity ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in transmembrane transport ISM
    Inferred from Sequence Model
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in membrane ISM
    Inferred from Sequence Model
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    SP1173
    Names
    CG10121-PA
    CG10121-PB
    CG10121-PC
    CG10121-PD
    SP1173-PA
    SP1173-PB
    SP1173-PC
    SP1173-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      6689327..6703521 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168177.3 → NP_729184.1  SP1173, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729184.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8H7, Q8MQS1, Q9NGV3
      Related
      FBpp0076667
      Conserved Domains (2) summary
      cl17781
      Location:552 → 632
      Chromate_transp; Chromate transporter
      cl21472
      Location:15 → 88
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

    2. NM_168178.2 → NP_729185.1  SP1173, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729185.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8H7, Q8MQS1, Q9NGV3
      Related
      FBpp0076668
      Conserved Domains (2) summary
      cl17781
      Location:552 → 632
      Chromate_transp; Chromate transporter
      cl21472
      Location:15 → 88
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

    3. NM_139796.3 → NP_648053.1  SP1173, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648053.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8H7, Q8MQS1, Q9NGV3
      Related
      FBpp0076670
      Conserved Domains (2) summary
      cl17781
      Location:552 → 632
      Chromate_transp; Chromate transporter
      cl21472
      Location:15 → 88
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...

    4. NM_168176.2 → NP_729183.1  SP1173, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729183.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E8H7, Q8MQS1, Q9NGV3
      Related
      FBpp0076669
      Conserved Domains (2) summary
      cl17781
      Location:552 → 632
      Chromate_transp; Chromate transporter
      cl21472
      Location:15 → 88
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0E8H7 Q0E8H7
    Q8MQS1 Q8MQS1
    Q9NGV3 Q9NGV3

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