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    CG1582 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32021, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG1582provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030246
    Locus tag
    Dmel_CG1582
    See related
    AllianceGenome:FB:FBgn0030246
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    cg1582; DHX57; Dmel\CG1582
    Summary
    Predicted to enable RNA binding activity and helicase activity. Is expressed in several structures, including embryonic/larval midgut; embryonic/larval midgut primordium; and mesoderm. Orthologous to human DHX57 (DExH-box helicase 57). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG1582 in Genome Data Viewer
    Location:
    9F8-9F8; 1-33 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (10894747..10899302, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (10788780..10793335, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR45617 Neighboring gene long non-coding RNA:CR44524 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identical functional organization of nonpolytene and polytene chromosomes in Drosophila melanogaster. Vatolina TY, et al. PLoS One, 2011. PMID 22022482, Free PMC Article
    2. DDX3X and specific initiation factors modulate FMR1 repeat-associated non-AUG-initiated translation. Linsalata AE, et al. EMBO Rep, 2019 Sep. PMID 31347257, Free PMC Article
    3. The Drosophila Translational Control Element (TCE) is required for high-level transcription of many genes that are specifically expressed in testes. Katzenberger RJ, et al. PLoS One, 2012. PMID 22984601, Free PMC Article
    4. Tracing the origin of the compensasome: evolutionary history of DEAH helicase and MYST acetyltransferase gene families. Sanjuán R, et al. Mol Biol Evol, 2001 Mar. PMID 11230534
    5. Characteristics of molecular-genetic organization of intercalary heterochromatin band 10A1-2 in X chromosome of Drosophila melanogaster. Babenko VN, et al. Dokl Biochem Biophys, 2009 Jan-Feb. PMID 19341102

    See all (31) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables RNA helicase activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables helicase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables helicase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG1582-PA
    CG1582-PB
    NP_001285098.1
    NP_572663.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      10894747..10899302 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001298169.1 → NP_001285098.1  uncharacterized protein Dmel_CG1582, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285098.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VZ55
      Conserved Domains (8) summary
      smart00490
      Location:781 → 871
      HELICc; helicase superfamily c-terminal domain
      smart00847
      Location:948 → 1029
      HA2; Helicase associated domain (HA2) Add an annotation
      COG1643
      Location:419 → 1206
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
      cd00046
      Location:471 → 619
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam00642
      Location:250 → 272
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      pfam05773
      Location:284 → 360
      RWD; RWD domain
      pfam07717
      Location:1070 → 1212
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
      cl21463
      Location:123 → 154
      UBA_like_SF; UBA domain-like superfamily

    2. NM_132435.2 → NP_572663.1  uncharacterized protein Dmel_CG1582, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572663.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VZ55
      Related
      FBpp0073259
      Conserved Domains (8) summary
      smart00490
      Location:781 → 871
      HELICc; helicase superfamily c-terminal domain
      smart00847
      Location:948 → 1029
      HA2; Helicase associated domain (HA2) Add an annotation
      COG1643
      Location:419 → 1206
      HrpA; HrpA-like RNA helicase [Translation, ribosomal structure and biogenesis]
      cd00046
      Location:471 → 619
      DEXDc; DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
      pfam00642
      Location:250 → 272
      zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)
      pfam05773
      Location:284 → 360
      RWD; RWD domain
      pfam07717
      Location:1070 → 1212
      OB_NTP_bind; Oligonucleotide/oligosaccharide-binding (OB)-fold
      cl21463
      Location:123 → 154
      UBA_like_SF; UBA domain-like superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9VZ55 Q9VZ55

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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