DCLRE1B DNA cross-link repair 1B [Gallus gallus (chicken)] - Gene

Summary

Symbol: DCLRE1Bprovided by CGNC
Full Name: DNA cross-link repair 1Bprovided by CGNC
Primary source: CGNC:66552
See related: Ensembl:ENSGALG00010027405
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: SNM1B
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 26

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	26	NC_052557.1 (3811003..3813848)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	26	NC_052598.1 (3779077..3781914)

Chromosome 26 - NC_052557.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables 5'-3' DNA exonuclease activity	IEA Inferred from Electronic Annotation more info	PubMed
enables damaged DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in double-strand break repair via nonhomologous end joining	IEA Inferred from Electronic Annotation more info	PubMed
involved_in interstrand cross-link repair	IEA Inferred from Electronic Annotation more info	PubMed
involved_in protection from non-homologous end joining at telomere	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: 5' exonuclease Apollo

Names: DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae); SNM1 homolog B; beta-lactamase MBLAC2

NP_001026671.3

EC 3.5.2.6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001031500.3 → NP_001026671.3 5' exonuclease Apollo

Status: VALIDATED

Source sequence(s)

AY376897

UniProtKB/TrEMBL

A0A8V1ABW9

Related

ENSGALP00010040717.1, ENSGALT00010066453.1

Conserved Domains (3) summary

cd11662
Location:505 → 539

apollo_TRF2_binding; TRF2-binding region of apollo and similar proteins

pfam07522
Location:291 → 374

DRMBL; DNA repair metallo-beta-lactamase

cd16273
Location:89 → 227

SNM1A-1C-like_MBL-fold; SNM1A , artemis/SNM1C, yeast Pso2p, and related proteins; MBL-fold metallo-hydrolase domain