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    RTEL1 regulator of telomere elongation helicase 1 [ Gallus gallus (chicken) ]

    Gene ID: 419262, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RTEL1provided by CGNC
    Official Full Name
    regulator of telomere elongation helicase 1provided by CGNC
    Primary source
    CGNC:4595
    See related
    Ensembl:ENSGALG00010024973
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    RTEL1-TNFRSF6B
    Orthologs
    human mouse all
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    Genomic context

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    See RTEL1 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    38
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 20 NC_052551.1 (10000709..10037564, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 20 NC_052592.1 (9782419..9819318, complement)

    Chromosome 20 - NC_052551.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124417339 Neighboring gene TNF receptor superfamily member 6b Neighboring gene microRNA 1798 Neighboring gene stathmin 3 Neighboring gene glucocorticoid modulatory element binding protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA helicase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables DNA polymerase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in DNA duplex unwinding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in DNA recombination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of DNA recombination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of t-circle formation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of double-strand break repair via homologous recombination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in telomeric loop disassembly IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    regulator of telomere elongation helicase 1
    Names
    RTEL1-TNFRSF6B readthrough (NMD candidate)
    helicase-like protein NHL
    XP_004947187.2
    XP_015152087.2
    XP_024998207.2
    XP_024998208.2
    XP_024998209.2
    XP_024998210.2
    XP_040506900.1
    XP_040506901.1
    XP_040544088.1
    XP_040544089.1
    XP_040544090.1
    XP_040544091.1
    XP_040544092.1
    XP_040544093.1
    XP_040544094.1
    XP_040544096.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052551.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      10000709..10037564 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040650967.2 → XP_040506901.1  regulator of telomere elongation helicase 1 isoform X6

      Conserved Domains (2) summary
      cd13932
      Location:885 → 988
      HN_RTEL1; harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL)
      TIGR00604
      Location:10 → 744
      rad3; DNA repair helicase (rad3)

    2. XM_015296601.4 → XP_015152087.2  regulator of telomere elongation helicase 1 isoform X3

      Conserved Domains (2) summary
      cd13932
      Location:885 → 988
      HN_RTEL1; harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL)
      TIGR00604
      Location:10 → 744
      rad3; DNA repair helicase (rad3)

    3. XM_040650966.2 → XP_040506900.1  regulator of telomere elongation helicase 1 isoform X5

      UniProtKB/TrEMBL
      A0A8V1A8N8
      Related
      ENSGALP00010037731.1, ENSGALT00010060988.1
      Conserved Domains (2) summary
      cd13932
      Location:886 → 989
      HN_RTEL1; harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL)
      TIGR00604
      Location:10 → 744
      rad3; DNA repair helicase (rad3)

    4. XM_004947130.5 → XP_004947187.2  regulator of telomere elongation helicase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZVY2
      Related
      ENSGALP00010037725.1, ENSGALT00010060980.1
      Conserved Domains (2) summary
      cd13932
      Location:886 → 989
      HN_RTEL1; harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL)
      TIGR00604
      Location:10 → 744
      rad3; DNA repair helicase (rad3)

    5. XM_025142441.3 → XP_024998209.2  regulator of telomere elongation helicase 1 isoform X7

      Conserved Domains (2) summary
      cd13932
      Location:908 → 1011
      HN_RTEL1; harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL)
      TIGR00604
      Location:10 → 744
      rad3; DNA repair helicase (rad3)

    6. XM_025142440.3 → XP_024998208.2  regulator of telomere elongation helicase 1 isoform X4

      Conserved Domains (2) summary
      cd13932
      Location:908 → 1011
      HN_RTEL1; harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL)
      TIGR00604
      Location:10 → 744
      rad3; DNA repair helicase (rad3)

    7. XM_025142439.3 → XP_024998207.2  regulator of telomere elongation helicase 1 isoform X1

      Conserved Domains (2) summary
      cd13932
      Location:908 → 1011
      HN_RTEL1; harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL)
      TIGR00604
      Location:10 → 744
      rad3; DNA repair helicase (rad3)

    8. XM_025142442.3 → XP_024998210.2  regulator of telomere elongation helicase 1 isoform X8

      Conserved Domains (2) summary
      cd13932
      Location:908 → 1011
      HN_RTEL1; harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL)
      TIGR00604
      Location:10 → 744
      rad3; DNA repair helicase (rad3)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052592.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      9782419..9819318 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040688159.2 → XP_040544093.1  regulator of telomere elongation helicase 1 isoform X6

      Conserved Domains (2) summary
      cd13932
      Location:885 → 988
      HN_RTEL1; harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL)
      TIGR00604
      Location:10 → 744
      rad3; DNA repair helicase (rad3)

    2. XM_040688156.2 → XP_040544090.1  regulator of telomere elongation helicase 1 isoform X3

      Conserved Domains (2) summary
      cd13932
      Location:885 → 988
      HN_RTEL1; harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL)
      TIGR00604
      Location:10 → 744
      rad3; DNA repair helicase (rad3)

    3. XM_040688158.2 → XP_040544092.1  regulator of telomere elongation helicase 1 isoform X5

      Conserved Domains (2) summary
      cd13932
      Location:886 → 989
      HN_RTEL1; harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL)
      TIGR00604
      Location:10 → 744
      rad3; DNA repair helicase (rad3)

    4. XM_040688155.2 → XP_040544089.1  regulator of telomere elongation helicase 1 isoform X2

      Conserved Domains (2) summary
      cd13932
      Location:886 → 989
      HN_RTEL1; harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL)
      TIGR00604
      Location:10 → 744
      rad3; DNA repair helicase (rad3)

    5. XM_040688160.2 → XP_040544094.1  regulator of telomere elongation helicase 1 isoform X7

      Conserved Domains (2) summary
      cd13932
      Location:908 → 1011
      HN_RTEL1; harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL)
      TIGR00604
      Location:10 → 744
      rad3; DNA repair helicase (rad3)

    6. XM_040688157.2 → XP_040544091.1  regulator of telomere elongation helicase 1 isoform X4

      Conserved Domains (2) summary
      cd13932
      Location:908 → 1011
      HN_RTEL1; harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL)
      TIGR00604
      Location:10 → 744
      rad3; DNA repair helicase (rad3)

    7. XM_040688154.2 → XP_040544088.1  regulator of telomere elongation helicase 1 isoform X1

      Conserved Domains (2) summary
      cd13932
      Location:908 → 1011
      HN_RTEL1; harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL)
      TIGR00604
      Location:10 → 744
      rad3; DNA repair helicase (rad3)

    8. XM_040688162.2 → XP_040544096.1  regulator of telomere elongation helicase 1 isoform X8

      Conserved Domains (2) summary
      cd13932
      Location:908 → 1011
      HN_RTEL1; harmonin_N_like domain of regulator of telomere elongation helicase 1 (also known as RTEL)
      TIGR00604
      Location:10 → 744
      rad3; DNA repair helicase (rad3)
    Nucleotide Protein Strain
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