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    LGI1 leucine rich glioma inactivated 1 [ Gallus gallus (chicken) ]

    Gene ID: 423802, updated on 3-Dec-2024

    Summary

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    Symbol
    LGI1provided by CGNC
    Full Name
    leucine rich glioma inactivated 1provided by CGNC
    Primary source
    CGNC:66461
    See related
    Ensembl:ENSGALG00010020295
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See LGI1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 6 NC_052537.1 (21092609..21124319, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 6 NC_052578.1 (20984029..21015692, complement)

    Chromosome 6 - NC_052537.1Genomic Context describing neighboring genes Neighboring gene phospholipase C epsilon 1 Neighboring gene protein SPT2 homolog Neighboring gene solute carrier family 35 member G1 Neighboring gene FRA10A associated CGG repeat 1 Neighboring gene phosphodiesterase 6C Neighboring gene retinol binding protein 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    leucine-rich glioma-inactivated protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044655.4 → NP_001038120.2  leucine-rich glioma-inactivated protein 1 precursor

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000232
      UniProtKB/TrEMBL
      A0A1D5PFF3, A0A1D5PMD5, A0A8V0ZE10, Q1EGJ8
      Conserved Domains (5) summary
      TIGR00864
      Location:138 → 213
      PCC; polycystin cation channel protein
      sd00031
      Location:109 → 132
      LRR_1; leucine-rich repeat [structural motif]
      sd00033
      Location:63 → 84
      LRR_RI; leucine-rich repeat [structural motif]
      pfam03736
      Location:496 → 535
      EPTP; EPTP domain
      pfam13855
      Location:107 → 167
      LRR_8; Leucine rich repeat

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052537.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      21092609..21124319 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046942921.1 → XP_046798877.1  leucine-rich glioma-inactivated protein 1 isoform X14

    2. XM_046942922.1 → XP_046798878.1  leucine-rich glioma-inactivated protein 1 isoform X15

    3. XM_046942918.1 → XP_046798874.1  leucine-rich glioma-inactivated protein 1 isoform X10

      UniProtKB/TrEMBL
      A0A8V0ZK48

    4. XM_046942919.1 → XP_046798875.1  leucine-rich glioma-inactivated protein 1 isoform X11

      UniProtKB/TrEMBL
      A0A8V0ZK48

    5. XM_046942920.1 → XP_046798876.1  leucine-rich glioma-inactivated protein 1 isoform X12

      UniProtKB/TrEMBL
      A0A8V0ZK48

    6. XM_046942913.1 → XP_046798869.1  leucine-rich glioma-inactivated protein 1 isoform X6

      UniProtKB/TrEMBL
      A0A8V0ZK48
      Related
      ENSGALP00010028969.1, ENSGALT00010048999.1

    7. XM_046942914.1 → XP_046798870.1  leucine-rich glioma-inactivated protein 1 isoform X7

      UniProtKB/TrEMBL
      A0A8V0Z6V0

    8. XM_046942915.1 → XP_046798871.1  leucine-rich glioma-inactivated protein 1 isoform X8

      UniProtKB/TrEMBL
      A0A8V0ZE10

    9. XM_046942908.1 → XP_046798864.1  leucine-rich glioma-inactivated protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZE10

    10. XM_046942909.1 → XP_046798865.1  leucine-rich glioma-inactivated protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZDN9, A0A8V0ZE10
      Related
      ENSGALP00010028967.1, ENSGALT00010048997.1

    11. XM_046942910.1 → XP_046798866.1  leucine-rich glioma-inactivated protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZDN5, A0A8V0ZE10
      Related
      ENSGALP00010028962.1, ENSGALT00010048991.1

    12. XM_046942906.1 → XP_046798862.1  leucine-rich glioma-inactivated protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5PFF3, A0A1D5PMD5, A0A8V0ZE10, Q1EGJ8
      Related
      ENSGALP00010028956.1, ENSGALT00010048983.1

    13. XM_046942911.1 → XP_046798867.1  leucine-rich glioma-inactivated protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZDN9, A0A8V0ZE10

    14. XM_046942905.1 → XP_046798861.1  leucine-rich glioma-inactivated protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5PFF3, A0A1D5PMD5, A0A8V0ZE10, Q1EGJ8

    15. XM_046942907.1 → XP_046798863.1  leucine-rich glioma-inactivated protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5PFF3, A0A1D5PMD5, A0A8V0ZE10, Q1EGJ8
      Related
      ENSGALP00010028965.1, ENSGALT00010048994.1

    16. XM_015288607.4 → XP_015144093.1  leucine-rich glioma-inactivated protein 1 isoform X16

      Conserved Domains (4) summary
      TIGR00864
      Location:35 → 110
      PCC; polycystin cation channel protein
      sd00031
      Location:6 → 29
      LRR_1; leucine-rich repeat [structural motif]
      pfam03736
      Location:393 → 432
      EPTP; EPTP domain
      pfam13855
      Location:4 → 64
      LRR_8; Leucine rich repeat

    17. XM_046942917.1 → XP_046798873.1  leucine-rich glioma-inactivated protein 1 isoform X9

      UniProtKB/TrEMBL
      A0A8V0ZDJ6

    18. XM_046942912.1 → XP_046798868.1  leucine-rich glioma-inactivated protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A8V0ZDJ6
      Related
      ENSGALP00010028942.1, ENSGALT00010048964.1

    19. XM_015288606.4 → XP_015144092.1  leucine-rich glioma-inactivated protein 1 isoform X13

      UniProtKB/TrEMBL
      A0A8V0Z6V0
      Conserved Domains (5) summary
      smart00082
      Location:84 → 132
      LRRCT; Leucine rich repeat C-terminal domain
      sd00031
      Location:28 → 51
      LRR_1; leucine-rich repeat [structural motif]
      pfam03736
      Location:228 → 274
      EPTP; EPTP domain
      pfam12799
      Location:26 → 66
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:26 → 84
      LRR_8; Leucine rich repeat

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052578.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      20984029..21015692 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046920268.1 → XP_046776224.1  leucine-rich glioma-inactivated protein 1 isoform X14

    2. XM_046920269.1 → XP_046776225.1  leucine-rich glioma-inactivated protein 1 isoform X15

    3. XM_046920264.1 → XP_046776220.1  leucine-rich glioma-inactivated protein 1 isoform X10

      UniProtKB/TrEMBL
      A0A8V0ZK48

    4. XM_046920265.1 → XP_046776221.1  leucine-rich glioma-inactivated protein 1 isoform X11

      UniProtKB/TrEMBL
      A0A8V0ZK48

    5. XM_046920266.1 → XP_046776222.1  leucine-rich glioma-inactivated protein 1 isoform X12

      UniProtKB/TrEMBL
      A0A8V0ZK48

    6. XM_046920260.1 → XP_046776216.1  leucine-rich glioma-inactivated protein 1 isoform X6

      UniProtKB/TrEMBL
      A0A8V0ZK48

    7. XM_046920261.1 → XP_046776217.1  leucine-rich glioma-inactivated protein 1 isoform X7

      UniProtKB/TrEMBL
      A0A8V0Z6V0

    8. XM_046920262.1 → XP_046776218.1  leucine-rich glioma-inactivated protein 1 isoform X8

      UniProtKB/TrEMBL
      A0A8V0ZE10

    9. XM_046920255.1 → XP_046776211.1  leucine-rich glioma-inactivated protein 1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0ZE10

    10. XM_046920256.1 → XP_046776212.1  leucine-rich glioma-inactivated protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZDN9, A0A8V0ZE10

    11. XM_046920257.1 → XP_046776213.1  leucine-rich glioma-inactivated protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0ZDN5, A0A8V0ZE10

    12. XM_046920252.1 → XP_046776208.1  leucine-rich glioma-inactivated protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5PFF3, A0A1D5PMD5, A0A8V0ZE10, Q1EGJ8

    13. XM_046920254.1 → XP_046776210.1  leucine-rich glioma-inactivated protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5PFF3, A0A1D5PMD5, A0A8V0ZE10, Q1EGJ8

    14. XM_046920253.1 → XP_046776209.1  leucine-rich glioma-inactivated protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5PFF3, A0A1D5PMD5, A0A8V0ZE10, Q1EGJ8

    15. XM_046920258.1 → XP_046776214.1  leucine-rich glioma-inactivated protein 1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0ZDN9, A0A8V0ZE10

    16. XM_046920251.1 → XP_046776207.1  leucine-rich glioma-inactivated protein 1 isoform X1

      UniProtKB/TrEMBL
      A0A1D5PFF3, A0A1D5PMD5, A0A8V0ZE10, Q1EGJ8

    17. XM_046920270.1 → XP_046776226.1  leucine-rich glioma-inactivated protein 1 isoform X16

    18. XM_046920263.1 → XP_046776219.1  leucine-rich glioma-inactivated protein 1 isoform X9

      UniProtKB/TrEMBL
      A0A8V0ZDJ6

    19. XM_046920259.1 → XP_046776215.1  leucine-rich glioma-inactivated protein 1 isoform X5

      UniProtKB/TrEMBL
      A0A8V0ZDJ6

    20. XM_046920267.1 → XP_046776223.1  leucine-rich glioma-inactivated protein 1 isoform X13

      UniProtKB/TrEMBL
      A0A8V0Z6V0
    Nucleotide Protein Strain
    Heading Accession and Version

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