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    IRF2 interferon regulatory factor 2 [ Gallus gallus (chicken) ]

    Gene ID: 396115, updated on 3-Dec-2024

    Summary

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    Symbol
    IRF2provided by CGNC
    Full Name
    interferon regulatory factor 2provided by CGNC
    Primary source
    CGNC:8084
    See related
    Ensembl:ENSGALG00010007130
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    IRF-2
    Orthologs
    human mouse all
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    Genomic context

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    See IRF2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (39087465..39136738)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (39035071..39084353)

    Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene centromere protein U Neighboring gene primase and DNA directed polymerase Neighboring gene caspase 3 Neighboring gene uncharacterized LOC121110735 Neighboring gene ectonucleotide pyrophosphatase/phosphodiesterase 6 Neighboring gene storkhead box 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cloning of chicken interferon regulatory factor-2 (IRF-2) cDNA: expression and mapping of the IRF-2 gene. Marienfeld R, et al. J Interferon Cytokine Res, 1997 Apr. PMID 9142651
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in immune system process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    interferon regulatory factor 2
    Names
    regulatory factor 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205196.1 → NP_990527.1  interferon regulatory factor 2

      See identical proteins and their annotated locations for NP_990527.1

      Status: PROVISIONAL

      Source sequence(s)
      X95478
      UniProtKB/Swiss-Prot
      Q98925
      UniProtKB/TrEMBL
      A0A8V0XMT4
      Conserved Domains (1) summary
      pfam00605
      Location:7 → 112
      IRF; Interferon regulatory factor transcription factor

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      39087465..39136738
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040698744.2 → XP_040554678.1  interferon regulatory factor 2 isoform X4

      UniProtKB/Swiss-Prot
      Q98925
      UniProtKB/TrEMBL
      A0A8V0XMT4
      Conserved Domains (1) summary
      pfam00605
      Location:7 → 112
      IRF; Interferon regulatory factor transcription factor

    2. XM_046939928.1 → XP_046795884.1  interferon regulatory factor 2 isoform X4

      UniProtKB/Swiss-Prot
      Q98925
      UniProtKB/TrEMBL
      A0A8V0XMT4

    3. XM_046939926.1 → XP_046795882.1  interferon regulatory factor 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XMT4

    4. XM_046939927.1 → XP_046795883.1  interferon regulatory factor 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XMT4

    5. XM_046939925.1 → XP_046795881.1  interferon regulatory factor 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XMT4

    6. XM_015276155.4 → XP_015131641.1  interferon regulatory factor 2 isoform X4

      UniProtKB/Swiss-Prot
      Q98925
      UniProtKB/TrEMBL
      A0A8V0XMT4
      Related
      ENSGALP00010009503.1, ENSGALT00010016981.1
      Conserved Domains (1) summary
      pfam00605
      Location:7 → 112
      IRF; Interferon regulatory factor transcription factor

    7. XM_015276154.4 → XP_015131640.1  interferon regulatory factor 2 isoform X4

      UniProtKB/Swiss-Prot
      Q98925
      UniProtKB/TrEMBL
      A0A8V0XMT4
      Conserved Domains (1) summary
      pfam00605
      Location:7 → 112
      IRF; Interferon regulatory factor transcription factor

    8. XM_046939933.1 → XP_046795889.1  interferon regulatory factor 2 isoform X6

      UniProtKB/TrEMBL
      A0A8V0XMT4

    9. XM_015276156.4 → XP_015131642.1  interferon regulatory factor 2 isoform X4

      UniProtKB/Swiss-Prot
      Q98925
      UniProtKB/TrEMBL
      A0A8V0XMT4
      Conserved Domains (1) summary
      pfam00605
      Location:7 → 112
      IRF; Interferon regulatory factor transcription factor

    10. XM_046939930.1 → XP_046795886.1  interferon regulatory factor 2 isoform X4

      UniProtKB/Swiss-Prot
      Q98925
      UniProtKB/TrEMBL
      A0A8V0XMT4

    11. XM_046939929.1 → XP_046795885.1  interferon regulatory factor 2 isoform X4

      UniProtKB/Swiss-Prot
      Q98925
      UniProtKB/TrEMBL
      A0A8V0XMT4

    12. XM_046939924.1 → XP_046795880.1  interferon regulatory factor 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XMT4, A0A8V0XU27
      Related
      ENSGALP00010009498.1, ENSGALT00010016969.1

    13. XM_040698742.2 → XP_040554676.1  interferon regulatory factor 2 isoform X1

      UniProtKB/TrEMBL
      A0A452J803
      Related
      ENSGALP00010009497.1, ENSGALT00010016967.1
      Conserved Domains (1) summary
      smart00348
      Location:73 → 179
      IRF; interferon regulatory factor

    14. XM_046939932.1 → XP_046795888.1  interferon regulatory factor 2 isoform X6

      UniProtKB/TrEMBL
      A0A8V0XMT4

    15. XM_046939931.1 → XP_046795887.1  interferon regulatory factor 2 isoform X5

      UniProtKB/TrEMBL
      A0A8V0XMT4

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      39035071..39084353
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046915570.1 → XP_046771526.1  interferon regulatory factor 2 isoform X4

      UniProtKB/Swiss-Prot
      Q98925
      UniProtKB/TrEMBL
      A0A8V0XMT4

    2. XM_046915571.1 → XP_046771527.1  interferon regulatory factor 2 isoform X4

      UniProtKB/Swiss-Prot
      Q98925
      UniProtKB/TrEMBL
      A0A8V0XMT4

    3. XM_046915566.1 → XP_046771522.1  interferon regulatory factor 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XMT4

    4. XM_046915567.1 → XP_046771523.1  interferon regulatory factor 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XMT4

    5. XM_046915565.1 → XP_046771521.1  interferon regulatory factor 2 isoform X3

      UniProtKB/TrEMBL
      A0A8V0XMT4

    6. XM_046915568.1 → XP_046771524.1  interferon regulatory factor 2 isoform X4

      UniProtKB/Swiss-Prot
      Q98925
      UniProtKB/TrEMBL
      A0A8V0XMT4

    7. XM_046915569.1 → XP_046771525.1  interferon regulatory factor 2 isoform X4

      UniProtKB/Swiss-Prot
      Q98925
      UniProtKB/TrEMBL
      A0A8V0XMT4

    8. XM_046915577.1 → XP_046771533.1  interferon regulatory factor 2 isoform X6

      UniProtKB/TrEMBL
      A0A8V0XMT4

    9. XM_046915572.1 → XP_046771528.1  interferon regulatory factor 2 isoform X4

      UniProtKB/Swiss-Prot
      Q98925
      UniProtKB/TrEMBL
      A0A8V0XMT4

    10. XM_046915574.1 → XP_046771530.1  interferon regulatory factor 2 isoform X4

      UniProtKB/Swiss-Prot
      Q98925
      UniProtKB/TrEMBL
      A0A8V0XMT4

    11. XM_046915573.1 → XP_046771529.1  interferon regulatory factor 2 isoform X4

      UniProtKB/Swiss-Prot
      Q98925
      UniProtKB/TrEMBL
      A0A8V0XMT4

    12. XM_046915564.1 → XP_046771520.1  interferon regulatory factor 2 isoform X2

      UniProtKB/TrEMBL
      A0A8V0XMT4, A0A8V0XU27

    13. XM_046915563.1 → XP_046771519.1  interferon regulatory factor 2 isoform X1

      UniProtKB/TrEMBL
      A0A452J803

    14. XM_046915576.1 → XP_046771532.1  interferon regulatory factor 2 isoform X6

      UniProtKB/TrEMBL
      A0A8V0XMT4

    15. XM_046915575.1 → XP_046771531.1  interferon regulatory factor 2 isoform X5

      UniProtKB/TrEMBL
      A0A8V0XMT4
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q98925.1 GenPept UniProtKB/Swiss-Prot:Q98925

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