PFDN1 prefoldin subunit 1 [Gallus gallus (chicken)] - Gene

Summary

Symbol: PFDN1provided by CGNC
Full Name: prefoldin subunit 1provided by CGNC
Primary source: CGNC:626
See related: Ensembl:ENSGALG00010008750
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 13

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	13	NC_052544.1 (287346..329949)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	13	NC_052585.1 (495090..537685)

Chromosome 13 - NC_052544.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein folding chaperone	IEA Inferred from Electronic Annotation more info	PubMed
enables unfolded protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in protein folding	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
part_of prefoldin complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: prefoldin subunit 1

Names: prefoldin 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001277146.2 → NP_001264075.1 prefoldin subunit 1 isoform 1

Status: VALIDATED

Description

Transcript Variant: This variant (1) encodes isoform 1.

Source sequence(s)

JAENSK010000254

UniProtKB/TrEMBL

F1NDS5

Related

ENSGALP00010011972.1, ENSGALT00010020767.1

Conserved Domains (1) summary

pfam01920
Location:14 → 117

Prefoldin_2; Prefoldin subunit
NM_001277147.1 → NP_001264076.1 prefoldin subunit 1 isoform 2

Status: VALIDATED

Description

Transcript Variant: This variant (2) contains an alternate exon, which results in a frameshift, compared to variant 1. The resulting protein (isoform 2) is longer and has a distinct C-terminus, compared to isoform 1.

Source sequence(s)

JAENSK010000254

UniProtKB/TrEMBL

A0A1D5PB69

Related

ENSGALP00010011968.1, ENSGALT00010020753.1

Conserved Domains (1) summary

pfam01920
Location:14 → 96

Prefoldin_2; Prefoldin subunit
NM_001277148.2 → NP_001264077.1 prefoldin subunit 1 isoform 3

Status: VALIDATED

Description

Transcript Variant: This variant (3) uses an alternate in-frame donor splice site in the coding region compared to variant 1. It encodes isoform 3, which is shorter compared to isoform 1.

Source sequence(s)

JAENSK010000254

UniProtKB/TrEMBL

A0A1L1RWG0

Conserved Domains (1) summary

cl09111
Location:14 → 110

Prefoldin; Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...

RNA

NR_102330.1 RNA Sequence

Status: VALIDATED

Description

Transcript Variant: This variant (4) uses two alternate internal exons compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

BX930867, BX934471, JAENSK010000254

Related

ENSGALT00010020758.1
NR_102331.1 RNA Sequence

Status: VALIDATED

Description

Transcript Variant: This variant (5) uses an alternate internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

BX930402, BX934471, JAENSK010000254
NR_102332.1 RNA Sequence

Status: VALIDATED

Description

Transcript Variant: This variant (6) uses an alternate internal exon compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

CN227307, JAENSK010000254