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    DSTN destrin, actin depolymerizing factor [ Gallus gallus (chicken) ]

    Gene ID: 396539, updated on 17-Aug-2024

    Summary

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    Symbol
    DSTNprovided by CGNC
    Full Name
    destrin, actin depolymerizing factorprovided by CGNC
    Primary source
    CGNC:6580
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    DSN; ACTDP
    Orthologs
    human mouse all
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    Genomic context

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    See DSTN in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (15242580..15253973, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (15156837..15168214, complement)

    Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene sorting nexin 5 Neighboring gene ribosome binding protein 1 Neighboring gene uncharacterized LOC124418353 Neighboring gene microRNA 3526 Neighboring gene cystatin C

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Nucleotide sequence and expression of a cDNA encoding chick brain actin depolymerizing factor. Adams ME, et al. Biochemistry, 1990 Aug 14. PMID 2223773
    2. Sequence of cDNAs encoding actin depolymerizing factor and cofilin of embryonic chicken skeletal muscle: two functionally distinct actin-regulatory proteins exhibit high structural homology. Abe H, et al. Biochemistry, 1990 Aug 14. PMID 1699599
    3. Expression of actin-binding proteins and requirement for actin-depolymerizing factor in chick neural crest cells. Vermillion KL, et al. Dev Dyn, 2014 May. PMID 24868596, Free PMC Article
    4. Proteomic studies of Syk-interacting proteins using a novel amine-specific isotope tag and GFP nanotrap. Galan JA, et al. J Am Soc Mass Spectrom, 2011 Feb. PMID 21472591, Free PMC Article
    5. Conserved BK channel-protein interactions reveal signals relevant to cell death and survival. Sokolowski B, et al. PLoS One, 2011. PMID 22174833, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables actin filament binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin filament fragmentation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in actin filament severing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell motility IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin cortical patch IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    destrin
    Names
    ADF
    actin depolymerizing factor

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205528.2 → NP_990859.2  destrin

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000062
      UniProtKB/Swiss-Prot
      P18359, Q5ZLP1
      Conserved Domains (1) summary
      cd11286
      Location:3 → 152
      ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      15242580..15253973 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      15156837..15168214 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P18359.3 GenPept UniProtKB/Swiss-Prot:P18359

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.