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    PPP2CA protein phosphatase 2 catalytic subunit alpha [ Gallus gallus (chicken) ]

    Gene ID: 416318, updated on 17-Aug-2024

    Summary

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    Symbol
    PPP2CAprovided by CGNC
    Full Name
    protein phosphatase 2 catalytic subunit alphaprovided by CGNC
    Primary source
    CGNC:4870
    See related
    Ensembl:ENSGALG00010015861
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See PPP2CA in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 13 NC_052544.1 (15487686..15503237)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 13 NC_052585.1 (15499503..15515054)

    Chromosome 13 - NC_052544.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121106748 Neighboring gene uncharacterized LOC112533436 Neighboring gene ubiquitin conjugating enzyme E2 B Neighboring gene uncharacterized LOC107054556 Neighboring gene S-phase kinase-associated protein 1 Neighboring gene transcription factor 7 (T-cell specific, HMG-box) Neighboring gene uncharacterized LOC124417180

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Regulation of PP2A activity by Mid1 controls cranial neural crest speed and gangliogenesis. Latta EJ, et al. Mech Dev, 2012 Jan-Feb. PMID 22285438
    2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Suppression of Mid1 function in r2 elevates PP2Ac protein, whilst ectopic expression of Mid1 depletes PP2Ac protein.
      Title: Regulation of PP2A activity by Mid1 controls cranial neural crest speed and gangliogenesis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in peptidyl-serine dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform
    Names
    protein phosphatase 2, catalytic subunit, alpha isozyme
    NP_001006152.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001006152.2 → NP_001006152.1  serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

      See identical proteins and their annotated locations for NP_001006152.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000256
      UniProtKB/TrEMBL
      A0A8V0Y3H9, Q5ZM47
      Related
      ENSGALP00010022055.1, ENSGALT00010038213.1
      Conserved Domains (1) summary
      cd07415
      Location:9 → 293
      MPP_PP2A_PP4_PP6; PP2A, PP4, and PP6 phosphoprotein phosphatases, metallophosphatase domain

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052544.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      15487686..15503237
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052585.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      15499503..15515054
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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