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    MYSM1 Myb like, SWIRM and MPN domains 1 [ Gallus gallus (chicken) ]

    Gene ID: 424671, updated on 3-Dec-2024

    Summary

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    Symbol
    MYSM1provided by CGNC
    Full Name
    Myb like, SWIRM and MPN domains 1provided by CGNC
    Primary source
    CGNC:8259
    See related
    Ensembl:ENSGALG00010026780
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See MYSM1 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 8 NC_052539.1 (26011417..26026349, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 8 NC_052580.1 (26024611..26039550, complement)

    Chromosome 8 - NC_052539.1Genomic Context describing neighboring genes Neighboring gene OMA1 zinc metallopeptidase Neighboring gene ankyrin-3-like Neighboring gene tumor associated calcium signal transducer 2 Neighboring gene FGGY carbohydrate kinase domain containing Neighboring gene Jun proto-oncogene, AP-1 transcription factor subunit

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables metallopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables polyubiquitin modification-dependent protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in double-strand break repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of BRCA1-A complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of BRISC complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone H2A deubiquitinase MYSM1
    Names
    2A-DUB
    myb-like, SWIRM and MPN domain-containing protein 1
    NP_001012945.2
    XP_015146508.2
    XP_015146509.2
    XP_040560616.1
    XP_040560617.1
    XP_046778804.1
    XP_046778805.1
    XP_046778806.1
    XP_046778807.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012927.2 → NP_001012945.2  histone H2A deubiquitinase MYSM1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000239
      UniProtKB/Swiss-Prot
      Q5F3F2
      Related
      ENSGALP00010039677.1, ENSGALT00010064975.1
      Conserved Domains (3) summary
      cd08067
      Location:573 → 755
      MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
      COG5259
      Location:382 → 466
      RSC8; RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription]
      cd00167
      Location:121 → 164
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052539.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      26011417..26026349 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015291023.4 → XP_015146509.2  histone H2A deubiquitinase MYSM1 isoform X2

      UniProtKB/Swiss-Prot
      Q5F3F2
      Conserved Domains (3) summary
      cd08067
      Location:573 → 742
      MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
      COG5259
      Location:382 → 466
      RSC8; RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription]
      cd00167
      Location:121 → 164
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

    2. XM_040704682.2 → XP_040560616.1  histone H2A deubiquitinase MYSM1 isoform X3

      UniProtKB/Swiss-Prot
      Q5F3F2
      UniProtKB/TrEMBL
      A0A8V1A6G0
      Related
      ENSGALP00010039676.1, ENSGALT00010064972.1
      Conserved Domains (3) summary
      cd08067
      Location:573 → 730
      MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
      COG5259
      Location:382 → 466
      RSC8; RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription]
      cd00167
      Location:121 → 164
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

    3. XM_015291022.4 → XP_015146508.2  histone H2A deubiquitinase MYSM1 isoform X1

      UniProtKB/Swiss-Prot
      Q5F3F2
      Conserved Domains (3) summary
      cd08067
      Location:573 → 755
      MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
      COG5259
      Location:382 → 466
      RSC8; RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription]
      cd00167
      Location:121 → 164
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

    4. XM_040704683.2 → XP_040560617.1  histone H2A deubiquitinase MYSM1 isoform X4

      UniProtKB/Swiss-Prot
      Q5F3F2
      Conserved Domains (3) summary
      cd08067
      Location:573 → 755
      MPN_2A_DUB; Mov34/MPN/PAD-1 family: Histone H2A deubiquitinase
      COG5259
      Location:382 → 466
      RSC8; RSC chromatin remodeling complex subunit RSC8 [Chromatin structure and dynamics / Transcription]
      cd00167
      Location:121 → 164
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052580.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      26024611..26039550 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046922849.1 → XP_046778805.1  histone H2A deubiquitinase MYSM1 isoform X2

      UniProtKB/Swiss-Prot
      Q5F3F2

    2. XM_046922850.1 → XP_046778806.1  histone H2A deubiquitinase MYSM1 isoform X3

      UniProtKB/Swiss-Prot
      Q5F3F2

    3. XM_046922848.1 → XP_046778804.1  histone H2A deubiquitinase MYSM1 isoform X1

      UniProtKB/Swiss-Prot
      Q5F3F2

    4. XM_046922851.1 → XP_046778807.1  histone H2A deubiquitinase MYSM1 isoform X4

      UniProtKB/Swiss-Prot
      Q5F3F2
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5F3F2.1 GenPept UniProtKB/Swiss-Prot:Q5F3F2

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