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    pir2 C2H2-type zinc finger domain-containing protein [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2541143, updated on 18-Sep-2024

    Summary

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    Official Symbol
    pir2
    Official Full Name
    C2H2-type zinc finger domain-containing protein
    Primary source
    PomBase:SPBC725.08
    Locus tag
    SPOM_SPBC725.08
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    ars2
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    Genomic context

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    See pir2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003423.3 (1219405..1221590)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene peroxisomal targeting signal receptor Pex5 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene BAR adaptor protein Hob3 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural analysis of Red1 as a conserved scaffold of the RNA-targeting MTREC/PAXT complex. Foucher AE, et al. Nat Commun, 2022 Aug 24. PMID 36002457, Free PMC Article
    2. Conserved protein Pir2(ARS2) mediates gene repression through cryptic introns in lncRNAs. Thillainadesan G, et al. Nat Commun, 2020 May 15. PMID 32415063, Free PMC Article
    3. Ubiquitination-dependent control of sexual differentiation in fission yeast. Simonetti F, et al. Elife, 2017 Aug 25. PMID 28841135, Free PMC Article
    4. The fission yeast MTREC complex targets CUTs and unspliced pre-mRNAs to the nuclear exosome. Zhou Y, et al. Nat Commun, 2015 May 20. PMID 25989903, Free PMC Article
    5. Enhancer of Rudimentary Cooperates with Conserved RNA-Processing Factors to Promote Meiotic mRNA Decay and Facultative Heterochromatin Assembly. Sugiyama T, et al. Mol Cell, 2016 Mar 3. PMID 26942678, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables lncRNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    NOT involved_in CUT catabolic process EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in nuclear polyadenylation-dependent CUT catabolic process IC
    Inferred by Curator
    more info
    		  
    NOT involved_in nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in regulatory ncRNA-mediated gene silencing EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in regulatory ncRNA-mediated heterochromatin formation ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of MTREC complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in chromatin EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nuclear body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nuclear body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    C2H2-type zinc finger domain-containing protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1219405..1221590
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021399.3 → NP_595488.1  C2H2-type zinc finger domain-containing protein [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595488.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O94326
      Conserved Domains (2) summary
      pfam04959
      Location:473 → 526
      ARS2; Arsenite-resistance protein 2
      pfam12066
      Location:109 → 179
      DUF3546; Domain of unknown function (DUF3546)
    Nucleotide Protein
    Heading Accession and Version

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