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    ppp1 pescadillo-family ribosome biogenesis protein [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540659, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ppp1
    Official Full Name
    pescadillo-family ribosome biogenesis protein
    Primary source
    PomBase:SPBC19F5.05c
    Locus tag
    SPOM_SPBC19F5.05C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    SPBC25D12.01c
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    Genomic context

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    See ppp1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003423.3 (3711419..3713657, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene U3 snoRNP protein Utp4 Neighboring gene ncRNA Neighboring gene inositol polyphosphate phosphatase Neighboring gene aspartate kinase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene nucleolar protein Dnt1 Neighboring gene MCM complex subunit Mcm7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Potent, Reversible, and Specific Chemical Inhibitors of Eukaryotic Ribosome Biogenesis. Kawashima SA, et al. Cell, 2016 Oct 6. PMID 27667686, Free PMC Article
    2. The Nrd1-like protein Seb1 coordinates cotranscriptional 3' end processing and polyadenylation site selection. Lemay JF, et al. Genes Dev, 2016 Jul 1. PMID 27401558, Free PMC Article
    3. Clr4/Suv39 and RNA quality control factors cooperate to trigger RNAi and suppress antisense RNA. Zhang K, et al. Science, 2011 Mar 25. PMID 21436456, Free PMC Article
    4. Chromatin localization of nucleophosmin organizes ribosome biogenesis. Ugolini I, et al. Mol Cell, 2022 Dec 1. PMID 36423630, Free PMC Article
    5. Nucleocytoplasmic transport in the midzone membrane domain controls yeast mitotic spindle disassembly. Lucena R, et al. J Cell Biol, 2015 May 11. PMID 25963819, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in assembly of large subunit precursor of preribosome EXP
    Inferred from Experiment
    more info
    		 PubMed 
    involved_in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of PeBoW complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleolus HDA PubMed 
    is_active_in nucleolus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    part_of preribosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of preribosome, large subunit precursor IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    pescadillo-family ribosome biogenesis protein

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3711419..3713657 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022464.3 → NP_596543.1  pescadillo-family ribosome biogenesis protein [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596543.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O60164, Q9US84
      Conserved Domains (3) summary
      smart00292
      Location:352 → 428
      BRCT; breast cancer carboxy-terminal domain
      COG5163
      Location:2 → 607
      NOP7; Protein required for biogenesis of the 60S ribosomal subunit [Translation, ribosomal structure and biogenesis]
      pfam06732
      Location:8 → 274
      Pescadillo_N; Pescadillo N-terminus
    Nucleotide Protein
    Heading Accession and Version

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