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    mas5 DNAJ domain-containing protein Mas5 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2539671, updated on 18-Sep-2024

    Summary

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    Official Symbol
    mas5
    Official Full Name
    DNAJ domain-containing protein Mas5
    Primary source
    PomBase:SPBC1734.11
    Locus tag
    SPOM_SPBC1734.11
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See mas5 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (1081375..1083347)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene NST UDP-N-acetylglucosamine transporter Neighboring gene mRNA processing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene dolichyl-P-Man:Man(7)GlcNAc(2)-PP-dolichyl-alpha-1,6-mannosyltransferase Neighboring gene ncRNA Neighboring gene F1-ATPase gamma subunit atp3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Hsp40 Mas5 Connects Protein Quality Control and the General Stress Response through the Thermo-sensitive Pyp1. Boronat S, et al. iScience, 2020 Nov 20. PMID 33225241, Free PMC Article
    2. RNAi-dependent heterochromatin assembly in fission yeast Schizosaccharomyces pombe requires heat-shock molecular chaperones Hsp90 and Mas5. Okazaki K, et al. Epigenetics Chromatin, 2018 Jun 4. PMID 29866182, Free PMC Article
    3. Monothiol glutaredoxin Grx5 interacts with Fe-S scaffold proteins Isa1 and Isa2 and supports Fe-S assembly and DNA integrity in mitochondria of fission yeast. Kim KD, et al. Biochem Biophys Res Commun, 2010 Feb 12. PMID 20085751
    4. Hsp70-Hsp40 chaperone complex functions in controlling polarized growth by repressing Hsf1-driven heat stress-associated transcription. Vjestica A, et al. PLoS Genet, 2013. PMID 24146635, Free PMC Article
    5. Tfg3, a subunit of the general transcription factor TFIIF in Schizosaccharomyces pombe, functions under stress conditions. Kimura M, et al. Nucleic Acids Res, 2004. PMID 15616156, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables Hsp70 protein binding ISM
    Inferred from Sequence Model
    more info
    		  
    enables protein sequestering activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables protein-folding chaperone binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables unfolded protein binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to heat IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cytoplasm protein quality control IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein aggregate center assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein refolding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein refolding IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in protein refolding IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in protein aggregate center IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DNAJ domain-containing protein Mas5

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      1081375..1083347
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021336.3 → NP_595428.1  DNAJ domain-containing protein Mas5 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_595428.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O74752
      Conserved Domains (4) summary
      cd10719
      Location:137 → 202
      DnaJ_zf; Zinc finger domain of DnaJ and HSP40
      cd10747
      Location:108 → 331
      DnaJ_C; C-terminal substrate binding domain of DnaJ and HSP40
      COG0484
      Location:2 → 357
      DnaJ; DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones]
      pfam00226
      Location:7 → 65
      DnaJ; DnaJ domain
    Nucleotide Protein
    Heading Accession and Version

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