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    rga3 Rho-type GTPase-activating protein Rga3 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542306, updated on 18-Sep-2024

    Summary

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    Official Symbol
    rga3
    Official Full Name
    Rho-type GTPase-activating protein Rga3
    Primary source
    PomBase:SPAC29A4.11
    Locus tag
    SPOM_SPAC29A4.11
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See rga3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (5123328..5129033, complement)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene peroxin-3 peroxisome import protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene urease accessory protein ure6 Neighboring gene uncharacterized protein Neighboring gene protein mug108 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene RNA polymerase I upstream activation factor complex subunit Rrn5 Neighboring gene ncRNA Neighboring gene rRNA exonuclease Rrp17

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Differential GAP requirement for Cdc42-GTP polarization during proliferation and sexual reproduction. Gallo Castro D, et al. J Cell Biol, 2018 Dec 3. PMID 30279276, Free PMC Article
    2. High-throughput knockout screen in Schizosaccharomyces pombe identifies a novel gene required for efficient homolog disjunction during meiosis I. Rumpf C, et al. Cell Cycle, 2010 May. PMID 20404563, Free PMC Article
    3. Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library. Ding DQ, et al. Genes Cells, 2000 Mar. PMID 10759889
    4. A non-transcriptional role for the glucocorticoid receptor in mediating the cell stress response. Ptushkina M, et al. Sci Rep, 2017 Sep 21. PMID 28935859, Free PMC Article
    5. A Proteome-wide Fission Yeast Interactome Reveals Network Evolution Principles from Yeasts to Human. Vo TV, et al. Cell, 2016 Jan 14. PMID 26771498, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables GTPase activator activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables small GTPase binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in small GTPase-mediated signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell cortex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cell cortex of cell tip HDA PubMed 
    is_active_in cell division site HDA PubMed 
    is_active_in cell division site IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cell division site IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cell tip HDA PubMed 
    is_active_in cell tip IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cortical dynamic polarity patch IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in growing cell tip IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in site of polarized growth IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Rho-type GTPase-activating protein Rga3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      5123328..5129033 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020300.3 → NP_594871.1  Rho-type GTPase-activating protein Rga3 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594871.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14014, Q9USB8
      Conserved Domains (5) summary
      smart00132
      Location:18 → 74
      LIM; Zinc-binding domain present in Lin-11, Isl-1, Mec-3
      smart00324
      Location:791 → 962
      RhoGAP; GTPase-activator protein for Rho-like GTPases
      COG5422
      Location:295 → 456
      ROM1; RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases [Signal transduction mechanisms]
      cd08368
      Location:78 → 128
      LIM; LIM is a small protein-protein interaction domain, containing two zinc fingers
      cd00029
      Location:698 → 740
      C1; protein kinase C conserved region 1 (C1 domain) superfamily
    Nucleotide Protein
    Heading Accession and Version

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