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    CG31495 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 261626, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG31495provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0051495
    Locus tag
    Dmel_CG31495
    See related
    AllianceGenome:FB:FBgn0051495
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG9931; Dmel\CG31495
    Summary
    Predicted to enable ATP hydrolysis activity. Predicted to be involved in Golgi to plasma membrane protein transport and intra-Golgi vesicle-mediated transport. Predicted to be active in Golgi stack. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 96. Orthologous to human NSF (N-ethylmaleimide sensitive factor, vesicle fusing ATPase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG31495 in Genome Data Viewer
    Location:
    87F15-87F15; 3-54 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (13838240..13839934, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (9663962..9665656, complement)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43300 Neighboring gene Male-specific RNA 87F Neighboring gene N-ethylmaleimide-sensitive factor 2 Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46239

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pri smORF Peptides Are Wide Mediators of Ecdysone Signaling, Contributing to Shape Spatiotemporal Responses. Dib A, et al. Front Genet, 2021. PMID 34527021, Free PMC Article
    2. Selective sweep analysis in the genomes of the 91-R and 91-C Drosophila melanogaster strains reveals few of the 'usual suspects' in dichlorodiphenyltrichloroethane (DDT) resistance. Steele LD, et al. PLoS One, 2015. PMID 25826265, Free PMC Article
    3. Peptides encoded by short ORFs control development and define a new eukaryotic gene family. Galindo MI, et al. PLoS Biol, 2007 May. PMID 17439302, Free PMC Article
    4. Age-dependent chromosomal distribution of male-biased genes in Drosophila. Zhang YE, et al. Genome Res, 2010 Nov. PMID 20798392, Free PMC Article
    5. A cautionary note for retrocopy identification: DNA-based duplication of intron-containing genes significantly contributes to the origination of single exon genes. Zhang YE, et al. Bioinformatics, 2011 Jul 1. PMID 21551137, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in Golgi to plasma membrane protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in SNARE complex disassembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in intra-Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi stack IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG31495-PA
    CG31495-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      13838240..13839934 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_169559.2 → NP_731866.1  uncharacterized protein Dmel_CG31495, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_731866.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8ING5
      Related
      FBpp0082345
      Conserved Domains (2) summary
      smart00382
      Location:129 → 259
      AAA; ATPases associated with a variety of cellular activities
      cl21455
      Location:129 → 257
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    2. NM_001300391.1 → NP_001287320.1  uncharacterized protein Dmel_CG31495, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001287320.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8ING5
      Conserved Domains (2) summary
      smart00382
      Location:129 → 259
      AAA; ATPases associated with a variety of cellular activities
      cl21455
      Location:129 → 257
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8ING5 Q8ING5

    Gene LinkOut

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