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    Ak6 Adenylate kinase 6 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36379, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ak6provided by FlyBase
    Official Full Name
    Adenylate kinase 6provided by FlyBase
    Primary source
    FLYBASE:FBgn0033754
    Locus tag
    Dmel_CG8816
    See related
    AllianceGenome:FB:FBgn0033754
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8816; DAK6; Dmel\CG8816
    Summary
    Enables adenylate kinase activity. Located in nucleus. Orthologous to human AK6 (adenylate kinase 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Ak6 in Genome Data Viewer
    Location:
    49B5-49B5; 2-67 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12569014..12569847, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8456519..8457352, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene frazzled Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Cytochrome P450 301a1 Neighboring gene stand still Neighboring gene Chloride channel-b Neighboring gene Sin3A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of a novel nuclear-localized adenylate kinase from Drosophila melanogaster. Meng G, et al. Biochemistry (Mosc), 2008 Jan. PMID 18294127
    2. Transcriptional response to dietary restriction in Drosophila melanogaster. Ding F, et al. J Insect Physiol, 2014 Oct. PMID 24819200, Free PMC Article
    3. Negative genetic correlation between longevity and its hormetic extension by dietary restriction in Drosophila melanogaster. Gomez FH, et al. Biogerontology, 2020 Apr. PMID 31786681
    4. mRNA-Associated Processes and Their Influence on Exon-Intron Structure in Drosophila melanogaster. Lepennetier G, et al. G3 (Bethesda), 2016 Jun 1. PMID 27172210, Free PMC Article
    5. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables ATP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables adenylate kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables adenylate kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables adenylate kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    adenylate kinase 6
    Names
    Ak6-PA
    CG8816-PA
    NP_610797.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      12569014..12569847 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_136953.4 → NP_610797.1  adenylate kinase 6 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610797.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q7JYV7
      Related
      FBpp0087004
      Conserved Domains (1) summary
      COG1936
      Location:10 → 173
      Fap7; Broad-specificity NMP kinase [Nucleotide transport and metabolism]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7JYV7.1 Q7JYV7

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