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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
Genomic
-
NG_051073.1 RefSeqGene
- Range
-
5116..119564
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
NM_001411020.1 → NP_001397949.1 son of sevenless homolog 2 isoform 2
Status: REVIEWED
- Source sequence(s)
-
AL109758
- Consensus CDS
-
CCDS91874.1
- UniProtKB/TrEMBL
-
B7ZKT5
- Related
- ENSP00000445328.1, ENST00000543680.5
-
NM_006939.4 → NP_008870.2 son of sevenless homolog 2 isoform 1
See identical proteins and their annotated locations for NP_008870.2
Status: REVIEWED
- Source sequence(s)
-
AI419975, AL109758, BC117261, R20624
- Consensus CDS
-
CCDS9697.1
- UniProtKB/Swiss-Prot
- B7ZKT6, D3DSB4, Q07890, Q15503, Q17RN1
- UniProtKB/TrEMBL
-
B7ZKT5
- Related
- ENSP00000216373.5, ENST00000216373.10
- Conserved Domains (6) summary
-
- smart00229
Location:595 → 739
- RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
- cd00155
Location:774 → 1013
- RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
- cd00160
Location:199 → 386
- RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
- cd01261
Location:437 → 543
- PH_SOS; Son of Sevenless (SOS) Pleckstrin homology (PH) domain
- pfam16768
Location:1023 → 1142
- NupH_GANP; Nucleoporin homology of Germinal-centre associated nuclear protein
- cl23830
Location:63 → 169
- Histone; Core histone H2A/H2B/H3/H4