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    GPR32 G protein-coupled receptor 32 [ Homo sapiens (human) ]

    Gene ID: 2854, updated on 9-Dec-2024

    Summary

    Official Symbol
    GPR32provided by HGNC
    Official Full Name
    G protein-coupled receptor 32provided by HGNC
    Primary source
    HGNC:HGNC:4487
    See related
    Ensembl:ENSG00000142511 MIM:603195; AllianceGenome:HGNC:4487
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    DRV1; RVDR1
    Summary
    This gene is intronless and encodes a member of the G-protein coupled receptor 1 family. The encoded protein binds to resolvin D1 and lipoxin A4 and has been linked to pulmonary inflammation. A related pseudogene has been identified on chromosome 19. [provided by RefSeq, Nov 2012]
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See GPR32 in Genome Data Viewer
    Location:
    19q13.33
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (50770464..50771732)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (53859268..53860536)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (51273721..51274989)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10975 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 10976 Neighboring gene CRISPRi-validated cis-regulatory element chr19.5690 Neighboring gene C-type lectin domain containing 11A Neighboring gene GPR32 pseudogene 1 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr19:51280870-51281694 Neighboring gene origin of replication 20mer1 Neighboring gene Sharpr-MPRA regulatory region 1509 Neighboring gene uncharacterized LOC105372439 Neighboring gene small integral membrane protein 47 Neighboring gene acid phosphatase 4

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    enables N-formyl peptide receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables complement receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in complement receptor mediated signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in inflammatory response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in phospholipase C-activating G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of cytosolic calcium ion concentration IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    probable G-protein coupled receptor 32
    Names
    resolvin D1 receptor

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001506.2NP_001497.1  probable G-protein coupled receptor 32

      See identical proteins and their annotated locations for NP_001497.1

      Status: REVIEWED

      Source sequence(s)
      AC010325, BC095544
      Consensus CDS
      CCDS12801.1
      UniProtKB/Swiss-Prot
      O75388, Q502U7, Q6NWS5
      UniProtKB/TrEMBL
      H9NIL6
      Related
      ENSP00000270590.3, ENST00000270590.4
      Conserved Domains (1) summary
      pfam00001
      Location:60316
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      50770464..50771732
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      53859268..53860536
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)