U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 [ Homo sapiens (human) ]

    Gene ID: 50807, updated on 3-Dec-2024

    Summary

    Official Symbol
    ASAP1provided by HGNC
    Official Full Name
    ArfGAP with SH3 domain, ankyrin repeat and PH domain 1provided by HGNC
    Primary source
    HGNC:HGNC:2720
    See related
    Ensembl:ENSG00000153317 MIM:605953; AllianceGenome:HGNC:2720
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PAP; PAG2; AMAP1; DDEF1; ZG14P; CENTB4
    Summary
    This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking and cytoskeleton remodeling. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
    Expression
    Ubiquitous expression in bone marrow (RPKM 18.3), spleen (RPKM 15.5) and 24 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ASAP1 in Genome Data Viewer
    Location:
    8q24.21-q24.22
    Exon count:
    41
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (130052104..130443674, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (131178779..131571038, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (131064350..131455920, complement)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene CYFIP related Rac1 interactor B Neighboring gene uncharacterized LOC124902025 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19542 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19543 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19544 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19545 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:131054337-131055152 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27979 Neighboring gene RNA, U7 small nuclear 181 pseudogene Neighboring gene ReSE screen-validated silencer GRCh37_chr8:131067248-131067450 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr8:131081877-131082759 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27980 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:131098365-131098897 Neighboring gene microRNA 5194 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:131110363-131110520 Neighboring gene RNA, U6 small nuclear 1255, pseudogene Neighboring gene ASAP1 intronic transcript 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27981 Neighboring gene small nucleolar RNA SNORA12 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr8:131216140-131217109 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27982 Neighboring gene uncharacterized LOC124902027 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27983 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27984 Neighboring gene NANOG hESC enhancer GRCh37_chr8:131323031-131323532 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27985 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27986 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19546 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:131345596-131346175 Neighboring gene ASAP1 intronic transcript 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:131370073-131371035 Neighboring gene uncharacterized LOC124902026 Neighboring gene NANOG-H3K4me1 hESC enhancer GRCh37_chr8:131380037-131380536 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:131388200-131388776 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:131431296-131431799 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19551 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19552 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19553 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19554 Neighboring gene Sharpr-MPRA regulatory region 3250 Neighboring gene uncharacterized LOC105375758 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr8:131540148-131541347 Neighboring gene NFE2L2 motif-containing MPRA enhancer 239 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27987 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27988 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_101181 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr8:131739458-131740657 Neighboring gene ReSE screen-validated silencer GRCh37_chr8:131759497-131759683 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 19555 Neighboring gene uncharacterized LOC105375762 Neighboring gene adenylate cyclase 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    EBI GWAS Catalog

    Description
    Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.
    EBI GWAS Catalog

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA1249

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables cadherin binding HDA PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylinositol-3,4,5-trisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylinositol-4,5-bisphosphate binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylserine binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Golgi membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in dendritic spine IEA
    Inferred from Electronic Annotation
    more info
     
    located_in glutamatergic synapse IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in podosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in trans-Golgi network membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
    Names
    130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein
    130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein
    ADP-ribosylation factor-directed GTPase-activating protein 1
    ARF GTPase-activating protein 1
    DEF-1
    PIP2-dependent ARF1 GAP
    centaurin, beta 4
    development and differentiation-enhancing factor 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_030354.1 RefSeqGene

      Range
      4987..396557
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001247996.2NP_001234925.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform 2

      See identical proteins and their annotated locations for NP_001234925.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) contains an additional exon (with an in-frame AUG) in the 5' region compared to variant 1. This results in translation initiation from an alternate start site, and a shorter isoform (2) with a distinct N-terminus compared to isoform 1.
      Source sequence(s)
      AB033075, AI494058, AP005856, BC144493, DA319233
      Consensus CDS
      CCDS75788.1
      UniProtKB/TrEMBL
      A0A0A0MRE5, H0YBF7
      Related
      ENSP00000350297.2, ENST00000357668.2
      Conserved Domains (8) summary
      cd07641
      Location:47261
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:10641120
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      cd00204
      Location:594682
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd13251
      Location:309415
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      pfam00169
      Location:319404
      PH; PH domain
      pfam01412
      Location:432548
      ArfGap; Putative GTPase activating protein for Arf
      pfam12796
      Location:575660
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:594627
      ANK; ANK repeat [structural motif]
    2. NM_001362924.1NP_001349853.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform 3

      Status: REVIEWED

      Source sequence(s)
      AB033075, AI494058, BC144493, BQ645913, DA315979, DA319233, DA416332
      UniProtKB/TrEMBL
      H0YBF7
      Conserved Domains (7) summary
      cd07641
      Location:54268
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:10741130
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      cd00204
      Location:604692
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd13251
      Location:319425
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:604637
      ANK; ANK repeat [structural motif]
      pfam01412
      Location:442558
      ArfGap; Putative GTPase activating protein for Arf
      cl26464
      Location:7271063
      Atrophin-1; Atrophin-1 family
    3. NM_001362925.2NP_001349854.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform 4

      Status: REVIEWED

      Source sequence(s)
      AB033075, AI494058, AP005856, BC144493, BG748866, DA315979, DA319233, DA416332
      UniProtKB/TrEMBL
      H0YBF7
      Conserved Domains (7) summary
      cd07641
      Location:54268
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:10171073
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      cd00204
      Location:604692
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd13251
      Location:319425
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:604637
      ANK; ANK repeat [structural motif]
      pfam01412
      Location:442558
      ArfGap; Putative GTPase activating protein for Arf
      cl26464
      Location:7301006
      Atrophin-1; Atrophin-1 family
    4. NM_001362926.2NP_001349855.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform 5

      Status: REVIEWED

      Source sequence(s)
      AB033075, AI494058, AP005856, BC144493, BG118567, BG748866, DA315979, DA319233, DA416332
      UniProtKB/TrEMBL
      H0YBF7
      Conserved Domains (7) summary
      cd07641
      Location:54268
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:10141070
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      cd00204
      Location:601689
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd13251
      Location:316422
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:601634
      ANK; ANK repeat [structural motif]
      pfam01412
      Location:439555
      ArfGap; Putative GTPase activating protein for Arf
      cl26464
      Location:7271003
      Atrophin-1; Atrophin-1 family
    5. NM_018482.4NP_060952.2  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform 1

      See identical proteins and their annotated locations for NP_060952.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the predominant transcript, and encodes isoform 1.
      Source sequence(s)
      AB033075, AI494058, AP005856, BC137135, DA319233
      Consensus CDS
      CCDS6362.1
      UniProtKB/Swiss-Prot
      B2RNV3, Q9ULH1
      UniProtKB/TrEMBL
      H0YBF7
      Related
      ENSP00000429900.1, ENST00000518721.6
      Conserved Domains (8) summary
      cd07641
      Location:54268
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:10711127
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      cd00204
      Location:601689
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd13251
      Location:316422
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      pfam00169
      Location:326411
      PH; PH domain
      pfam01412
      Location:439555
      ArfGap; Putative GTPase activating protein for Arf
      pfam12796
      Location:582667
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:601634
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

      Range
      130052104..130443674 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047421810.1XP_047277766.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X14

      UniProtKB/TrEMBL
      H0YBF7
    2. XM_047421806.1XP_047277762.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X11

      UniProtKB/TrEMBL
      H0YBF7
    3. XM_017013468.2XP_016868957.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X9

      UniProtKB/TrEMBL
      H0YBF7
      Conserved Domains (8) summary
      cd11965
      Location:10151071
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      cd00204
      Location:545633
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd13251
      Location:260366
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      pfam00169
      Location:270355
      PH; PH domain
      pfam01412
      Location:383499
      ArfGap; Putative GTPase activating protein for Arf
      pfam12796
      Location:526611
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:545578
      ANK; ANK repeat [structural motif]
      cl12013
      Location:1209
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    4. XM_047421804.1XP_047277760.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X10

      UniProtKB/TrEMBL
      H0YBF7
    5. XM_047421800.1XP_047277756.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X2

      UniProtKB/Swiss-Prot
      B2RNV3, Q9ULH1
      UniProtKB/TrEMBL
      H0YBF7
    6. XM_047421799.1XP_047277755.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      H0YBF7
    7. XM_047421805.1XP_047277761.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X10

      UniProtKB/TrEMBL
      H0YBF7
    8. XM_011517052.3XP_011515354.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011515354.1

      UniProtKB/TrEMBL
      H0YBF7
      Conserved Domains (7) summary
      cd07641
      Location:54268
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:10741130
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      cd00204
      Location:604692
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd13251
      Location:319425
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      sd00045
      Location:604637
      ANK; ANK repeat [structural motif]
      pfam01412
      Location:442558
      ArfGap; Putative GTPase activating protein for Arf
      cl26464
      Location:7271063
      Atrophin-1; Atrophin-1 family
    9. XM_047421807.1XP_047277763.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X11

      UniProtKB/TrEMBL
      H0YBF7
    10. XM_047421808.1XP_047277764.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X12

      UniProtKB/TrEMBL
      H0YBF7
    11. XM_047421801.1XP_047277757.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X4

      UniProtKB/TrEMBL
      A0A0A0MRE5, H0YBF7
    12. XM_011517053.2XP_011515355.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X3

      See identical proteins and their annotated locations for XP_011515355.1

      UniProtKB/TrEMBL
      H0YBF7
      Conserved Domains (8) summary
      cd07641
      Location:47261
      BAR_ASAP1; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with SH3 domain, ANK repeat and PH domain containing protein 1
      cd11965
      Location:10671123
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      cd00204
      Location:597685
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd13251
      Location:312418
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      pfam00169
      Location:322407
      PH; PH domain
      pfam01412
      Location:435551
      ArfGap; Putative GTPase activating protein for Arf
      pfam12796
      Location:578663
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:597630
      ANK; ANK repeat [structural motif]
    13. XM_006716565.3XP_006716628.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X7

      UniProtKB/TrEMBL
      H0YBF7
      Conserved Domains (8) summary
      cd11965
      Location:10181074
      SH3_ASAP1; Src homology 3 domain of ArfGAP with SH3 domain, ankyrin repeat and PH domain containing protein 1
      cd00204
      Location:548636
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      cd13251
      Location:263369
      PH_ASAP; ArfGAP with SH3 domain, ankyrin repeat and PH domain Pleckstrin homology (PH) domain
      pfam00169
      Location:273358
      PH; PH domain
      pfam01412
      Location:386502
      ArfGap; Putative GTPase activating protein for Arf
      pfam12796
      Location:529614
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:548581
      ANK; ANK repeat [structural motif]
      cl12013
      Location:1212
      BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
    14. XM_017013467.3XP_016868956.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X5

      UniProtKB/TrEMBL
      H0YBF7
    15. XM_047421809.1XP_047277765.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X13

      UniProtKB/TrEMBL
      H0YBF7
    16. XM_047421802.1XP_047277758.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X6

      UniProtKB/TrEMBL
      H0YBF7
    17. XM_047421803.1XP_047277759.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X8

      UniProtKB/TrEMBL
      H0YBF7
    18. XM_047421811.1XP_047277767.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X15

      UniProtKB/TrEMBL
      H0YBF7
      Related
      ENSP00000429391.1, ENST00000524124.5
    19. XM_047421812.1XP_047277768.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X16

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060932.1 Alternate T2T-CHM13v2.0

      Range
      131178779..131571038 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054360532.1XP_054216507.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X14

      UniProtKB/TrEMBL
      H0YBF7
    2. XM_054360528.1XP_054216503.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X11

      UniProtKB/TrEMBL
      H0YBF7
    3. XM_054360525.1XP_054216500.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X9

      UniProtKB/TrEMBL
      H0YBF7
    4. XM_054360526.1XP_054216501.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X10

      UniProtKB/TrEMBL
      H0YBF7
    5. XM_054360517.1XP_054216492.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      H0YBF7
    6. XM_054360515.1XP_054216490.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      H0YBF7
    7. XM_054360527.1XP_054216502.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X10

      UniProtKB/TrEMBL
      H0YBF7
    8. XM_054360516.1XP_054216491.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X1

      UniProtKB/TrEMBL
      H0YBF7
    9. XM_054360529.1XP_054216504.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X11

      UniProtKB/TrEMBL
      H0YBF7
    10. XM_054360518.1XP_054216493.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      H0YBF7
    11. XM_054360519.1XP_054216494.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X4

      UniProtKB/TrEMBL
      H0YBF7
    12. XM_054360530.1XP_054216505.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X12

      UniProtKB/TrEMBL
      H0YBF7
    13. XM_054360520.1XP_054216495.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X17

      UniProtKB/TrEMBL
      H0YBF7
    14. XM_054360523.1XP_054216498.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X7

      UniProtKB/TrEMBL
      H0YBF7
    15. XM_054360521.1XP_054216496.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X5

      UniProtKB/TrEMBL
      H0YBF7
    16. XM_054360531.1XP_054216506.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X13

      UniProtKB/TrEMBL
      H0YBF7
    17. XM_054360522.1XP_054216497.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X6

      UniProtKB/TrEMBL
      H0YBF7
    18. XM_054360524.1XP_054216499.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X8

      UniProtKB/TrEMBL
      H0YBF7
    19. XM_054360533.1XP_054216508.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X15

      UniProtKB/TrEMBL
      H0YBF7
    20. XM_054360534.1XP_054216509.1  arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform X16