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    Btnl10 butyrophilin-like 10 [ Mus musculus (house mouse) ]

    Gene ID: 192194, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Btnl10provided by MGI
    Official Full Name
    butyrophilin-like 10provided by MGI
    Primary source
    MGI:MGI:2182073
    See related
    Ensembl:ENSMUSG00000020490 AllianceGenome:MGI:2182073
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Butr1; BUTR-1
    Summary
    Predicted to enable signaling receptor binding activity. Predicted to be involved in T cell receptor signaling pathway and regulation of cytokine production. Predicted to be located in membrane. Predicted to be active in external side of plasma membrane. Is expressed in liver lobe. Orthologous to human BTNL10P (butyrophilin like 10, pseudogene). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in liver E14.5 (RPKM 10.9), liver E14 (RPKM 9.9) and 3 other tissues See more
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    Genomic context

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    See Btnl10 in Genome Data Viewer
    Location:
    11 B1.3; 11 36.37 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (58808703..58817791)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (58917877..58926965)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 39 Neighboring gene STARR-positive B cell enhancer ABC_E2990 Neighboring gene predicted gene 12257 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:58741489-58741672 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:58741803-58741956 Neighboring gene STARR-positive B cell enhancer ABC_E8409 Neighboring gene ring finger protein 187 Neighboring gene predicted gene, 51864 Neighboring gene STARR-positive B cell enhancer ABC_E3954 Neighboring gene H2B clustered histone 27

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (5) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in T cell receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of cytokine production IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    butyrophilin-like protein 10
    Names
    butyrophilin related 1
    butyrophilin-like protein BUTR-1

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001363414.1 → NP_001350343.1  butyrophilin-like protein 10 variant 1 precursor

      Status: VALIDATED

      Source sequence(s)
      AK143638, AL662809
      Consensus CDS
      CCDS88163.1
      Related
      ENSMUSP00000063279.7, ENSMUST00000069941.13
      Conserved Domains (3) summary
      cd05713
      Location:47 → 146
      Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
      cl02614
      Location:301 → 471
      SPRY; SPRY domain
      cl11960
      Location:151 → 229
      Ig; Immunoglobulin domain

    2. NM_138678.2 → NP_619619.2  butyrophilin-like protein 10 variant 2 precursor

      See identical proteins and their annotated locations for NP_619619.2

      Status: VALIDATED

      Source sequence(s)
      AL662809
      Consensus CDS
      CCDS24753.1
      UniProtKB/Swiss-Prot
      A2AB75, Q8C0U8, Q9JK39
      Related
      ENSMUSP00000020792.6, ENSMUST00000020792.12
      Conserved Domains (3) summary
      cd05713
      Location:47 → 146
      Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
      smart00410
      Location:39 → 145
      IG_like; Immunoglobulin like
      cl11960
      Location:152 → 231
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      58808703..58817791
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006532533.3 → XP_006532596.1  butyrophilin-like protein 10 isoform X1

      See identical proteins and their annotated locations for XP_006532596.1

      UniProtKB/Swiss-Prot
      Q9JK39
      Conserved Domains (3) summary
      cd05713
      Location:47 → 146
      Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
      cl02614
      Location:301 → 471
      SPRY; SPRY domain
      cl11960
      Location:151 → 229
      Ig; Immunoglobulin domain

    2. XM_006532534.3 → XP_006532597.1  butyrophilin-like protein 10 isoform X2

      Conserved Domains (3) summary
      cd05713
      Location:47 → 146
      Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
      pfam13765
      Location:303 → 351
      PRY; SPRY-associated domain
      cl11960
      Location:151 → 229
      Ig; Immunoglobulin domain

    3. XM_011248809.2 → XP_011247111.1  butyrophilin-like protein 10 isoform X3

      Conserved Domains (2) summary
      cd05713
      Location:47 → 146
      Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
      cl11960
      Location:151 → 229
      Ig; Immunoglobulin domain

    4. XM_006532535.5 → XP_006532598.1  butyrophilin-like protein 10 isoform X4

      Conserved Domains (2) summary
      cd05713
      Location:47 → 146
      Ig_MOG_like; Immunoglobulin (Ig)-like domain of myelin oligodendrocyte glycoprotein (MOG)
      cl11960
      Location:151 → 229
      Ig; Immunoglobulin domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9JK39.2 GenPept UniProtKB/Swiss-Prot:Q9JK39

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