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    Jakmip2 janus kinase and microtubule interacting protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 76217, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Jakmip2provided by MGI
    Official Full Name
    janus kinase and microtubule interacting protein 2provided by MGI
    Primary source
    MGI:MGI:1923467
    See related
    Ensembl:ENSMUSG00000024502 AllianceGenome:MGI:1923467
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6430702L21Rik; D930046L20Rik
    Summary
    Predicted to be located in Golgi apparatus. Is expressed in early conceptus; embryo; epiblast; and inner cell mass. Orthologous to human JAKMIP2 (janus kinase and microtubule interacting protein 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in CNS E18 (RPKM 8.1), CNS E14 (RPKM 5.7) and 5 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Jakmip2 in Genome Data Viewer
    Location:
    18 B3; 18 23.36 cM
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (43659261..43820850, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (43526196..43687785, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41714 Neighboring gene predicted gene 3650 Neighboring gene eukaryotic translation initiation factor 3, subunit J2 Neighboring gene STARR-seq mESC enhancer starr_44453 Neighboring gene STARR-seq mESC enhancer starr_44454 Neighboring gene serine peptidase inhibitor, Kazal type 1 Neighboring gene secretoglobin, family 3A, member 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Mammalian embryo comparison identifies novel pluripotency genes associated with the naïve or primed state. Bernardo AS, et al. Biol Open, 2018 Aug 17. PMID 30026265, Free PMC Article
    2. Activin A Determines Steroid Levels and Composition in the Fetal Testis. Whiley PAF, et al. Endocrinology, 2020 Jul 1. PMID 32274496
    3. Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders. Li J, et al. Nat Neurosci, 2017 Aug. PMID 28671696, Free PMC Article
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    janus kinase and microtubule-interacting protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163637.1 → NP_001157109.1  janus kinase and microtubule-interacting protein 2

      See identical proteins and their annotated locations for NP_001157109.1

      Status: VALIDATED

      Source sequence(s)
      AK133750, BC094439, BY635087, CJ149565
      Consensus CDS
      CCDS50271.1
      UniProtKB/TrEMBL
      D3YXK0
      Related
      ENSMUSP00000080881.7, ENSMUST00000082254.8
      Conserved Domains (2) summary
      COG1196
      Location:24 → 804
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam16034
      Location:410 → 602
      JAKMIP_CC3; JAKMIP CC3 domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      43659261..43820850 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006526338.4 → XP_006526401.1  janus kinase and microtubule-interacting protein 2 isoform X2

      Conserved Domains (2) summary
      COG1196
      Location:24 → 787
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam16034
      Location:409 → 581
      JAKMIP_CC3; JAKMIP CC3 domain

    2. XM_006526337.4 → XP_006526400.1  janus kinase and microtubule-interacting protein 2 isoform X1

      Conserved Domains (2) summary
      COG1196
      Location:24 → 804
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam16034
      Location:409 → 602
      JAKMIP_CC3; JAKMIP CC3 domain

    3. XM_006526340.5 → XP_006526403.1  janus kinase and microtubule-interacting protein 2 isoform X4

      Conserved Domains (3) summary
      COG1196
      Location:2 → 204
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:263 → 598
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:200 → 393
      JAKMIP_CC3; JAKMIP CC3 domain

    4. XM_011247034.4 → XP_011245336.1  janus kinase and microtubule-interacting protein 2 isoform X3

      Conserved Domains (2) summary
      COG1196
      Location:24 → 783
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam16034
      Location:410 → 581
      JAKMIP_CC3; JAKMIP CC3 domain

    5. XM_036161305.1 → XP_036017198.1  janus kinase and microtubule-interacting protein 2 isoform X5

      Conserved Domains (3) summary
      COG1196
      Location:2 → 204
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:263 → 548
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam16034
      Location:201 → 393
      JAKMIP_CC3; JAKMIP CC3 domain
    Nucleotide Protein Strain
    Heading Accession and Version

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