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    Git2 GIT ArfGAP 2 [ Mus musculus (house mouse) ]

    Gene ID: 26431, updated on 3-Dec-2024

    Summary

    Official Symbol
    Git2provided by MGI
    Official Full Name
    GIT ArfGAP 2provided by MGI
    Primary source
    MGI:MGI:1347053
    See related
    Ensembl:ENSMUSG00000041890 AllianceGenome:MGI:1347053
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CAT2; mKIAA0148; 1500036H07Rik; 5830420E16Rik; 6430510B20Rik; 9630056M03Rik; B230104M05Rik
    Summary
    Predicted to enable GTPase activator activity and small GTPase binding activity. Involved in presynaptic modulation of chemical synaptic transmission and regulation of synaptic vesicle exocytosis. Acts upstream of or within behavioral response to pain. Is active in calyx of Held. Is expressed in genitourinary system. Orthologous to human GIT2 (GIT ArfGAP 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in thymus adult (RPKM 38.4), lung adult (RPKM 24.5) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Git2 in Genome Data Viewer
    Location:
    5 F; 5 55.99 cM
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (114865469..114912647, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (114727408..114774588, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 34931 Neighboring gene STARR-positive B cell enhancer ABC_E10341 Neighboring gene trichoplein, keratin filament binding Neighboring gene microRNA 7028 Neighboring gene RIKEN cDNA 4930515G01 gene Neighboring gene STARR-positive B cell enhancer ABC_E3602 Neighboring gene ankyrin repeat domain 13a Neighboring gene STARR-positive B cell enhancer ABC_E3603 Neighboring gene STARR-seq mESC enhancer starr_14089 Neighboring gene RIKEN cDNA 1500011B03 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA0148

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein-containing complex binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables small GTPase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in calyx of Held IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in calyx of Held IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in presynapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    ARF GTPase-activating protein GIT2
    Names
    ARF GAP GIT2
    ARF GTPase activating protein 2
    G protein-coupled receptor kinase-interactor 2
    GRK-interacting protein 2
    cool-interacting tyrosine-phosphorylated protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077359.2NP_001070827.1  ARF GTPase-activating protein GIT2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
      Conserved Domains (6) summary
      smart00105
      Location:2124
      ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
      cd00204
      Location:109220
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam08518
      Location:267295
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:559673
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137229
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:137165
      ANK; ANK repeat [structural motif]
    2. NM_001077360.2NP_001070828.1  ARF GTPase-activating protein GIT2 isoform 3

      See identical proteins and their annotated locations for NP_001070828.1

      Status: VALIDATED

      Source sequence(s)
      AC087330
      Consensus CDS
      CCDS39223.1
      UniProtKB/TrEMBL
      J3QK07, Q6PGJ1, Q80XR8
      Related
      ENSMUSP00000039718.8, ENSMUST00000043283.14
      Conserved Domains (6) summary
      smart00105
      Location:2124
      ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
      cd00204
      Location:109220
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam08518
      Location:266294
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:558672
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137229
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:137165
      ANK; ANK repeat [structural motif]
    3. NM_001347400.2NP_001334329.1  ARF GTPase-activating protein GIT2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC087330
      Consensus CDS
      CCDS84939.1
      UniProtKB/TrEMBL
      E9PVA6, J3QK07
      Related
      ENSMUSP00000083754.5, ENSMUST00000086564.11
    4. NM_001429058.1NP_001415987.1  ARF GTPase-activating protein GIT2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    5. NM_001429059.1NP_001415988.1  ARF GTPase-activating protein GIT2 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    6. NM_001429060.1NP_001415989.1  ARF GTPase-activating protein GIT2 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    7. NM_001429061.1NP_001415990.1  ARF GTPase-activating protein GIT2 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    8. NM_001429062.1NP_001415991.1  ARF GTPase-activating protein GIT2 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    9. NM_001429063.1NP_001415992.1  ARF GTPase-activating protein GIT2 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    10. NM_001429064.1NP_001415993.1  ARF GTPase-activating protein GIT2 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    11. NM_001429065.1NP_001415994.1  ARF GTPase-activating protein GIT2 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    12. NM_001429066.1NP_001415995.1  ARF GTPase-activating protein GIT2 isoform 13

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    13. NM_001429067.1NP_001415996.1  ARF GTPase-activating protein GIT2 isoform 14

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    14. NM_001429068.1NP_001415997.1  ARF GTPase-activating protein GIT2 isoform 15

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    15. NM_001429069.1NP_001415998.1  ARF GTPase-activating protein GIT2 isoform 16

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    16. NM_001429070.1NP_001415999.1  ARF GTPase-activating protein GIT2 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    17. NM_001429071.1NP_001416000.1  ARF GTPase-activating protein GIT2 isoform 18

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    18. NM_001429072.1NP_001416001.1  ARF GTPase-activating protein GIT2 isoform 19

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    19. NM_001429073.1NP_001416002.1  ARF GTPase-activating protein GIT2 isoform 20

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    20. NM_001429074.1NP_001416003.1  ARF GTPase-activating protein GIT2 isoform 21

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    21. NM_001429075.1NP_001416004.1  ARF GTPase-activating protein GIT2 isoform 22

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    22. NM_001429076.1NP_001416005.1  ARF GTPase-activating protein GIT2 isoform 23

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    23. NM_001429077.1NP_001416006.1  ARF GTPase-activating protein GIT2 isoform 24

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    24. NM_001429078.1NP_001416007.1  ARF GTPase-activating protein GIT2 isoform 25

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    25. NM_001429079.1NP_001416008.1  ARF GTPase-activating protein GIT2 isoform 26

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    26. NM_001429080.1NP_001416009.1  ARF GTPase-activating protein GIT2 isoform 27

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    27. NM_001429081.1NP_001416010.1  ARF GTPase-activating protein GIT2 isoform 28

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    28. NM_001429082.1NP_001416011.1  ARF GTPase-activating protein GIT2 isoform 29

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    29. NM_001429083.1NP_001416012.1  ARF GTPase-activating protein GIT2 isoform 30

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    30. NM_001429084.1NP_001416013.1  ARF GTPase-activating protein GIT2 isoform 31

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    31. NM_001429085.1NP_001416014.1  ARF GTPase-activating protein GIT2 isoform 32

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    32. NM_001429086.1NP_001416015.1  ARF GTPase-activating protein GIT2 isoform 33

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    33. NM_001429087.1NP_001416016.1  ARF GTPase-activating protein GIT2 isoform 34

      Status: VALIDATED

      Source sequence(s)
      AC087330
      UniProtKB/TrEMBL
      J3QK07
    34. NM_019834.4NP_062808.3  ARF GTPase-activating protein GIT2 isoform 1

      See identical proteins and their annotated locations for NP_062808.3

      Status: VALIDATED

      Source sequence(s)
      AC087330
      Consensus CDS
      CCDS19570.2
      UniProtKB/Swiss-Prot
      E9QPU7, Q9JLQ2
      UniProtKB/TrEMBL
      J3QK07
      Related
      ENSMUSP00000107803.3, ENSMUST00000112185.9
      Conserved Domains (6) summary
      smart00105
      Location:2124
      ArfGap; Putative GTP-ase activating proteins for the small GTPase, ARF
      cd00204
      Location:109220
      ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
      pfam08518
      Location:265293
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:587701
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137229
      Ank_2; Ankyrin repeats (3 copies)
      sd00045
      Location:137165
      ANK; ANK repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      114865469..114912647 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006530331.4XP_006530394.1  ARF GTPase-activating protein GIT2 isoform X2

      UniProtKB/TrEMBL
      J3QK07
      Conserved Domains (6) summary
      sd00045
      Location:137165
      ANK; ANK repeat [structural motif]
      cd08847
      Location:1111
      ArfGap_GIT2; GIT2 GTPase activating protein for Arf
      pfam08518
      Location:267295
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:639753
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137229
      Ank_2; Ankyrin repeats (3 copies)
      pfam16559
      Location:415479
      GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
    2. XM_006530334.4XP_006530397.1  ARF GTPase-activating protein GIT2 isoform X4

      UniProtKB/TrEMBL
      J3QK07
      Conserved Domains (6) summary
      sd00045
      Location:137165
      ANK; ANK repeat [structural motif]
      cd08847
      Location:1111
      ArfGap_GIT2; GIT2 GTPase activating protein for Arf
      pfam08518
      Location:268296
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:625739
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137229
      Ank_2; Ankyrin repeats (3 copies)
      pfam16559
      Location:416465
      GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
    3. XM_006530335.4XP_006530398.1  ARF GTPase-activating protein GIT2 isoform X7

      UniProtKB/TrEMBL
      J3QK07
      Conserved Domains (6) summary
      sd00045
      Location:137165
      ANK; ANK repeat [structural motif]
      cd08847
      Location:1111
      ArfGap_GIT2; GIT2 GTPase activating protein for Arf
      pfam08518
      Location:268296
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:610724
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137229
      Ank_2; Ankyrin repeats (3 copies)
      pfam16559
      Location:416480
      GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
    4. XM_006530339.4XP_006530402.1  ARF GTPase-activating protein GIT2 isoform X1

      UniProtKB/TrEMBL
      J3QK07
      Conserved Domains (6) summary
      sd00045
      Location:137165
      ANK; ANK repeat [structural motif]
      cd08847
      Location:1111
      ArfGap_GIT2; GIT2 GTPase activating protein for Arf
      pfam08518
      Location:268296
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:640754
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137229
      Ank_2; Ankyrin repeats (3 copies)
      pfam16559
      Location:416480
      GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
    5. XM_030254527.1XP_030110387.1  ARF GTPase-activating protein GIT2 isoform X17

      Related
      ENSMUSP00000136796.2, ENSMUST00000178440.8
      Conserved Domains (5) summary
      sd00045
      Location:137165
      ANK; ANK repeat [structural motif]
      cd08847
      Location:1111
      ArfGap_GIT2; GIT2 GTPase activating protein for Arf
      pfam08518
      Location:265293
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:557671
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137229
      Ank_2; Ankyrin repeats (3 copies)
    6. XM_030254522.2XP_030110382.1  ARF GTPase-activating protein GIT2 isoform X6

      Conserved Domains (6) summary
      sd00045
      Location:137165
      ANK; ANK repeat [structural motif]
      cd08847
      Location:1111
      ArfGap_GIT2; GIT2 GTPase activating protein for Arf
      pfam08518
      Location:265293
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:622736
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137229
      Ank_2; Ankyrin repeats (3 copies)
      pfam16559
      Location:413462
      GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
    7. XM_006530333.5XP_006530396.1  ARF GTPase-activating protein GIT2 isoform X3

      Conserved Domains (6) summary
      sd00045
      Location:137165
      ANK; ANK repeat [structural motif]
      cd08847
      Location:1111
      ArfGap_GIT2; GIT2 GTPase activating protein for Arf
      pfam08518
      Location:265293
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:637751
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137229
      Ank_2; Ankyrin repeats (3 copies)
      pfam16559
      Location:413477
      GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
    8. XM_017320893.3XP_017176382.1  ARF GTPase-activating protein GIT2 isoform X12

      Conserved Domains (5) summary
      sd00045
      Location:137165
      ANK; ANK repeat [structural motif]
      cd08847
      Location:1111
      ArfGap_GIT2; GIT2 GTPase activating protein for Arf
      pfam08518
      Location:266294
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:588702
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137229
      Ank_2; Ankyrin repeats (3 copies)
    9. XM_030254520.2XP_030110380.1  ARF GTPase-activating protein GIT2 isoform X5

      Conserved Domains (6) summary
      sd00045
      Location:137165
      ANK; ANK repeat [structural motif]
      cd08847
      Location:1111
      ArfGap_GIT2; GIT2 GTPase activating protein for Arf
      pfam08518
      Location:266294
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:623737
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137229
      Ank_2; Ankyrin repeats (3 copies)
      pfam16559
      Location:414463
      GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
    10. XM_006530336.5XP_006530399.1  ARF GTPase-activating protein GIT2 isoform X8

      Conserved Domains (6) summary
      sd00045
      Location:137165
      ANK; ANK repeat [structural motif]
      cd08847
      Location:1111
      ArfGap_GIT2; GIT2 GTPase activating protein for Arf
      pfam08518
      Location:266294
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:608722
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137229
      Ank_2; Ankyrin repeats (3 copies)
      pfam16559
      Location:414478
      GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
    11. XM_006530338.5XP_006530401.1  ARF GTPase-activating protein GIT2 isoform X16

      UniProtKB/TrEMBL
      D3Z1I2, J3QK07
      Related
      ENSMUSP00000107801.2, ENSMUST00000112183.8
      Conserved Domains (5) summary
      sd00045
      Location:137165
      ANK; ANK repeat [structural motif]
      cd08847
      Location:1111
      ArfGap_GIT2; GIT2 GTPase activating protein for Arf
      pfam08518
      Location:268296
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:560674
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137229
      Ank_2; Ankyrin repeats (3 copies)
    12. XM_006530337.5XP_006530400.1  ARF GTPase-activating protein GIT2 isoform X11

      UniProtKB/TrEMBL
      J3QK07
      Conserved Domains (5) summary
      sd00045
      Location:137165
      ANK; ANK repeat [structural motif]
      cd08847
      Location:1111
      ArfGap_GIT2; GIT2 GTPase activating protein for Arf
      pfam08518
      Location:268296
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:590704
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137229
      Ank_2; Ankyrin repeats (3 copies)
    13. XM_030254524.2XP_030110384.1  ARF GTPase-activating protein GIT2 isoform X10

      UniProtKB/TrEMBL
      J3QK07
      Conserved Domains (6) summary
      sd00045
      Location:137165
      ANK; ANK repeat [structural motif]
      cd08847
      Location:1111
      ArfGap_GIT2; GIT2 GTPase activating protein for Arf
      pfam08518
      Location:268296
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:595709
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137229
      Ank_2; Ankyrin repeats (3 copies)
      pfam16559
      Location:416465
      GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
    14. XM_030254526.2XP_030110386.1  ARF GTPase-activating protein GIT2 isoform X15

      Conserved Domains (6) summary
      sd00045
      Location:75103
      ANK; ANK repeat [structural motif]
      cl28907
      Location:149
      ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
      pfam08518
      Location:203231
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:575689
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:75167
      Ank_2; Ankyrin repeats (3 copies)
      pfam16559
      Location:351415
      GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
    15. XM_036165144.1XP_036021037.1  ARF GTPase-activating protein GIT2 isoform X14

      Conserved Domains (6) summary
      sd00045
      Location:75103
      ANK; ANK repeat [structural motif]
      cl28907
      Location:149
      ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
      pfam08518
      Location:204232
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:574690
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:75167
      Ank_2; Ankyrin repeats (3 copies)
      pfam16559
      Location:352416
      GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
    16. XM_030254525.2XP_030110385.1  ARF GTPase-activating protein GIT2 isoform X13

      UniProtKB/TrEMBL
      J3QK07
      Conserved Domains (6) summary
      sd00045
      Location:75103
      ANK; ANK repeat [structural motif]
      cl28907
      Location:149
      ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
      pfam08518
      Location:206234
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:578692
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:75167
      Ank_2; Ankyrin repeats (3 copies)
      pfam16559
      Location:354418
      GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor
    17. XM_030254529.2XP_030110389.1  ARF GTPase-activating protein GIT2 isoform X19

      Conserved Domains (5) summary
      sd00045
      Location:75103
      ANK; ANK repeat [structural motif]
      cl28907
      Location:149
      ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
      pfam08518
      Location:203231
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:525639
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:75167
      Ank_2; Ankyrin repeats (3 copies)
    18. XM_030254530.2XP_030110390.1  ARF GTPase-activating protein GIT2 isoform X20

      Conserved Domains (5) summary
      sd00045
      Location:75103
      ANK; ANK repeat [structural motif]
      cl28907
      Location:149
      ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
      pfam08518
      Location:204232
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:496610
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:75167
      Ank_2; Ankyrin repeats (3 copies)
    19. XM_030254528.2XP_030110388.1  ARF GTPase-activating protein GIT2 isoform X18

      Conserved Domains (5) summary
      sd00045
      Location:75103
      ANK; ANK repeat [structural motif]
      cl28907
      Location:149
      ArfGap; GTPase-activating protein (GAP) for the ADP ribosylation factors (ARFs)
      pfam08518
      Location:204232
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:526640
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:75167
      Ank_2; Ankyrin repeats (3 copies)
    20. XM_030254523.2XP_030110383.1  ARF GTPase-activating protein GIT2 isoform X9

      Related
      ENSMUSP00000122302.3, ENSMUST00000155908.8
      Conserved Domains (6) summary
      sd00045
      Location:137165
      ANK; ANK repeat [structural motif]
      cd08847
      Location:1111
      ArfGap_GIT2; GIT2 GTPase activating protein for Arf
      pfam08518
      Location:265293
      GIT_SHD; Spa2 homology domain (SHD) of GIT
      pfam12205
      Location:607721
      GIT1_C; G protein-coupled receptor kinase-interacting protein 1 C term
      pfam12796
      Location:137229
      Ank_2; Ankyrin repeats (3 copies)
      pfam16559
      Location:413477
      GIT_CC; GIT coiled-coil Rho guanine nucleotide exchange factor