Tuba3b tubulin, alpha 3B [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Tuba3bprovided by MGI
Official Full Name: tubulin, alpha 3Bprovided by MGI
Primary source: MGI:MGI:1095408
See related: Ensembl:ENSMUSG00000067338 AllianceGenome:MGI:1095408
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: M[a]7; Tuba7
Summary: Acts upstream of or within male germ-line stem cell population maintenance. Predicted to be located in microtubule cytoskeleton. Is expressed in several structures, including gonad; liver; nervous system; sensory organ; and spleen. Human ortholog(s) of this gene implicated in keratoconus. Orthologous to several human genes including TUBA3C (tubulin alpha 3c) and TUBA3D (tubulin alpha 3d). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward testis adult (RPKM 866.7) See more
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Genomic context

Location:: 6 G3; 6 77.62 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	6	NC_000072.7 (145561689..145567203)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	6	NC_000072.6 (145615963..145621477)

Chromosome 6 - NC_000072.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within male germ-line stem cell population maintenance	IGI Inferred from Genetic Interaction more info	PubMed

Component	Evidence Code	Pubs
located_in microtubule cytoskeleton	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: tubulin alpha-3 chain

Names: alpha-tubulin 3/7; alpha-tubulin isotype M-alpha-3/7; tubulin alpha-3/alpha-7 chain; tubulin, alpha 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.