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    Tmem151b transmembrane protein 151B [ Mus musculus (house mouse) ]

    Gene ID: 210573, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Tmem151bprovided by MGI
    Official Full Name
    transmembrane protein 151Bprovided by MGI
    Primary source
    MGI:MGI:2685169
    See related
    Ensembl:ENSMUSG00000096847 AllianceGenome:MGI:2685169
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm323
    Summary
    Predicted to be active in membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; liver lobe; and thymus. Orthologous to human TMEM151B (transmembrane protein 151B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in cerebellum adult (RPKM 30.1), cortex adult (RPKM 20.2) and 9 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tmem151b in Genome Data Viewer
    Location:
    17 B3; 17 22.56 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (45852879..45860624, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (45541940..45549677, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated, serine-rich 1 Neighboring gene STARR-seq mESC enhancer starr_42624 Neighboring gene ribosomal protein L21 pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:45625569-45626099 Neighboring gene STARR-seq mESC enhancer starr_42626 Neighboring gene STARR-positive B cell enhancer ABC_E4215 Neighboring gene STARR-positive B cell enhancer ABC_E9052 Neighboring gene alanyl-tRNA synthetase 2, mitochondrial Neighboring gene t-complex-associated testis expressed 1 Neighboring gene STARR-positive B cell enhancer ABC_E7533 Neighboring gene STARR-positive B cell enhancer ABC_E961 Neighboring gene CapStarr-seq enhancer MGSCv37_chr17:45695258-45695367 Neighboring gene STARR-positive B cell enhancer ABC_E10954 Neighboring gene nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon Neighboring gene solute carrier family 35, member B2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. Sundberg JP, et al. PLoS One, 2017. PMID 28700664, Free PMC Article
    2. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
    3. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    4. Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Bedogni F, et al. Front Mol Neurosci, 2021. PMID 34321999, Free PMC Article
    5. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 151B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013749.3 → NP_001013771.1  transmembrane protein 151B

      See identical proteins and their annotated locations for NP_001013771.1

      Status: VALIDATED

      Source sequence(s)
      AC163677
      Consensus CDS
      CCDS28810.1
      UniProtKB/Swiss-Prot
      Q5XJV8, Q68FE7
      Related
      ENSMUSP00000136337.2, ENSMUST00000180252.3
      Conserved Domains (1) summary
      pfam14857
      Location:41 → 486
      TMEM151; TMEM151 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      45852879..45860624 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036160432.1 → XP_036016325.1  transmembrane protein 151B isoform X2

      Conserved Domains (1) summary
      pfam14857
      Location:1 → 421
      TMEM151; TMEM151 family

    2. XM_006523970.5 → XP_006524033.1  transmembrane protein 151B isoform X1

      Conserved Domains (1) summary
      pfam14857
      Location:70 → 516
      TMEM151; TMEM151 family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q68FE7.1 GenPept UniProtKB/Swiss-Prot:Q68FE7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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