U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    PTK2 protein tyrosine kinase 2 [ Gallus gallus (chicken) ]

    Gene ID: 396416, updated on 3-Dec-2024

    Summary

    Symbol
    PTK2provided by CGNC
    Full Name
    protein tyrosine kinase 2provided by CGNC
    Primary source
    CGNC:12089
    See related
    Ensembl:ENSGALG00010009159
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    FAK; FAK1; FRNK; p125FAK
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See PTK2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    45
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (144624642..144822877, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (144995925..145194150, complement)

    Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene microRNA 6572 Neighboring gene argonaute 2, RISC catalytic component Neighboring gene ribosomal protein lateral stalk subunit P1 Neighboring gene uncharacterized LOC121110141 Neighboring gene microRNA 1770

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables protein tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in signal complex assembly IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in focal adhesion IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    focal adhesion kinase 1
    Names
    FADK 1
    PTK2 protein tyrosine kinase 2
    focal adhesion kinase-related nonkinase
    p41/p43FRNK
    pp125FAK
    NP_001383479.1
    NP_001383480.1
    NP_001383481.1
    NP_001383482.1
    NP_001383483.1
    NP_001383484.1
    NP_001383485.1
    NP_001383486.1
    XP_046766445.1
    XP_046766446.1
    XP_046766447.1
    XP_046766448.1
    XP_046766449.1
    XP_046766450.1
    XP_046766452.1
    XP_046766453.1
    XP_046766454.1
    XP_046766455.1
    XP_046766456.1
    XP_046766457.1
    XP_046766458.1
    XP_046766459.1
    XP_046766460.1
    XP_046766461.1
    XP_046766462.1
    XP_046766463.1
    XP_046766464.1
    XP_046766465.1
    XP_046766466.1
    XP_046766467.1
    XP_046766468.1
    XP_046766469.1
    XP_046766470.1
    XP_046766471.1
    XP_046766472.1
    XP_046766473.1
    XP_046766474.1
    XP_046766475.1
    XP_046766476.1
    XP_046766477.1
    XP_046766478.1
    XP_046766479.1
    XP_046775221.1
    XP_046775232.1
    XP_046775243.1
    XP_046775244.1
    XP_046775246.1
    XP_046775247.1
    XP_046775248.1
    XP_046775250.1
    XP_046775252.1
    XP_046775253.1
    XP_046775254.1
    XP_046775256.1
    XP_046775258.1
    XP_046775264.1
    XP_046775269.1
    XP_046775274.1
    XP_046775279.1
    XP_046775283.1
    XP_046775286.1
    XP_046775296.1
    XP_046775307.1
    XP_046775315.1
    XP_046775322.1
    XP_046775324.1
    XP_046775329.1
    XP_046775332.1
    XP_046775336.1
    XP_046775340.1
    XP_046775347.1
    XP_046775351.1
    XP_046775352.1
    XP_046775353.1
    XP_046775354.1
    XP_046775356.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001396550.1NP_001383479.1  focal adhesion kinase 1 isoform a

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000044
      UniProtKB/TrEMBL
      A0A8V0Y0S6
      Conserved Domains (3) summary
      cd05056
      Location:461725
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:82304
      B41; Band 4.1 homologues
      cd13190
      Location:300410
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    2. NM_001396551.1NP_001383480.1  focal adhesion kinase 1 isoform b

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000044
      UniProtKB/TrEMBL
      A0A8V0Y0S1
      Related
      ENSGALP00010012543.1, ENSGALT00010021907.1
      Conserved Domains (3) summary
      cd05056
      Location:459723
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:80302
      B41; Band 4.1 homologues
      cd13190
      Location:298408
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    3. NM_001396552.1NP_001383481.1  focal adhesion kinase 1 isoform c

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000044
      UniProtKB/TrEMBL
      A0A8V0XWD5
      Conserved Domains (3) summary
      cd05056
      Location:428692
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36258
      B41; Band 4.1 homologues
      cd13190
      Location:254364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    4. NM_001396553.1NP_001383482.1  focal adhesion kinase 1 isoform d

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000044
      UniProtKB/TrEMBL
      A0A8V0Y517
      Conserved Domains (3) summary
      cd05056
      Location:422686
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36258
      B41; Band 4.1 homologues
      cd13190
      Location:254364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    5. NM_001396554.1NP_001383483.1  focal adhesion kinase 1 isoform e

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000044
      UniProtKB/TrEMBL
      A0A8V0Y512
      Conserved Domains (3) summary
      cd05056
      Location:415679
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36258
      B41; Band 4.1 homologues
      cd13190
      Location:254364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    6. NM_001396555.1NP_001383484.1  focal adhesion kinase 1 isoform e

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000044
      UniProtKB/TrEMBL
      A0A8V0Y512
      Related
      ENSGALP00010012583.1, ENSGALT00010021968.1
      Conserved Domains (3) summary
      cd05056
      Location:415679
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36258
      B41; Band 4.1 homologues
      cd13190
      Location:254364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    7. NM_001396556.1NP_001383485.1  focal adhesion kinase 1 isoform e

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000044
      UniProtKB/TrEMBL
      A0A8V0Y512
      Related
      ENSGALP00010012593.1, ENSGALT00010021982.1
      Conserved Domains (3) summary
      cd05056
      Location:415679
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36258
      B41; Band 4.1 homologues
      cd13190
      Location:254364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2
    8. NM_001396557.1NP_001383486.1  focal adhesion kinase 1 isoform e

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000044
      UniProtKB/TrEMBL
      A0A8V0Y512
      Related
      ENSGALP00010012598.1, ENSGALT00010021988.1
      Conserved Domains (3) summary
      cd05056
      Location:415679
      PTKc_FAK; Catalytic domain of the Protein Tyrosine Kinase, Focal Adhesion Kinase
      smart00295
      Location:36258
      B41; Band 4.1 homologues
      cd13190
      Location:254364
      FERM_C_FAK1; FERM domain C-lobe of Focal Adhesion Kinase 1 and 2

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      144624642..144822877 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046919359.1XP_046775315.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
    2. XM_046919376.1XP_046775332.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
    3. XM_046919380.1XP_046775336.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
    4. XM_046919351.1XP_046775307.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
      Related
      ENSGALP00010012572.1, ENSGALT00010021954.1
    5. XM_046919366.1XP_046775322.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
      Related
      ENSGALP00010012559.1, ENSGALT00010021936.1
    6. XM_046919373.1XP_046775329.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
    7. XM_046919368.1XP_046775324.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
    8. XM_046919384.1XP_046775340.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
    9. XM_046919290.1XP_046775246.1  focal adhesion kinase 1 isoform X5

      UniProtKB/TrEMBL
      A0A8V0XWD1
    10. XM_046919395.1XP_046775351.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
    11. XM_046919330.1XP_046775286.1  focal adhesion kinase 1 isoform X19

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    12. XM_046919327.1XP_046775283.1  focal adhesion kinase 1 isoform X18

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    13. XM_046919400.1XP_046775356.1  focal adhesion kinase 1 isoform X25

      UniProtKB/TrEMBL
      A0A8V0Y0S6, A0A8V0Y9A0
      Related
      ENSGALP00010012555.1, ENSGALT00010021932.1
    14. XM_046919294.1XP_046775250.1  focal adhesion kinase 1 isoform X8

      UniProtKB/TrEMBL
      A0A8V0Y0S6
      Related
      ENSGALP00010012548.1, ENSGALT00010021919.1
    15. XM_046919323.1XP_046775279.1  focal adhesion kinase 1 isoform X17

      UniProtKB/TrEMBL
      A0A8V0Y0S6, A0A8V0Y4W9
      Related
      ENSGALP00010012552.1, ENSGALT00010021927.1
    16. XM_046919318.1XP_046775274.1  focal adhesion kinase 1 isoform X16

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    17. XM_046919308.1XP_046775264.1  focal adhesion kinase 1 isoform X14

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    18. XM_046919300.1XP_046775256.1  focal adhesion kinase 1 isoform X12

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    19. XM_046919313.1XP_046775269.1  focal adhesion kinase 1 isoform X15

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    20. XM_046919302.1XP_046775258.1  focal adhesion kinase 1 isoform X13

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    21. XM_046919298.1XP_046775254.1  focal adhesion kinase 1 isoform X11

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    22. XM_046919297.1XP_046775253.1  focal adhesion kinase 1 isoform X10

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    23. XM_046919292.1XP_046775248.1  focal adhesion kinase 1 isoform X7

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    24. XM_046919287.1XP_046775243.1  focal adhesion kinase 1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    25. XM_046919291.1XP_046775247.1  focal adhesion kinase 1 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    26. XM_046919288.1XP_046775244.1  focal adhesion kinase 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    27. XM_046919276.1XP_046775232.1  focal adhesion kinase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    28. XM_046919265.1XP_046775221.1  focal adhesion kinase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    29. XM_046919391.1XP_046775347.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
    30. XM_046919340.1XP_046775296.1  focal adhesion kinase 1 isoform X20

      UniProtKB/TrEMBL
      A0A8V0Y0S1
    31. XM_046919296.1XP_046775252.1  focal adhesion kinase 1 isoform X9

      UniProtKB/TrEMBL
      A0A8V0Y0S1
    32. XM_046919397.1XP_046775353.1  focal adhesion kinase 1 isoform X23

    33. XM_046919396.1XP_046775352.1  focal adhesion kinase 1 isoform X22

    34. XM_046919398.1XP_046775354.1  focal adhesion kinase 1 isoform X24

      UniProtKB/TrEMBL
      Q92063

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      144995925..145194150 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046910511.1XP_046766467.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
    2. XM_046910515.1XP_046766471.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
    3. XM_046910516.1XP_046766472.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
    4. XM_046910510.1XP_046766466.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
    5. XM_046910512.1XP_046766468.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
    6. XM_046910514.1XP_046766470.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
    7. XM_046910513.1XP_046766469.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
    8. XM_046910517.1XP_046766473.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
    9. XM_046910493.1XP_046766449.1  focal adhesion kinase 1 isoform X5

      UniProtKB/TrEMBL
      A0A8V0XWD1
    10. XM_046910519.1XP_046766475.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
    11. XM_046910508.1XP_046766464.1  focal adhesion kinase 1 isoform X19

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    12. XM_046910507.1XP_046766463.1  focal adhesion kinase 1 isoform X18

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    13. XM_046910523.1XP_046766479.1  focal adhesion kinase 1 isoform X25

      UniProtKB/TrEMBL
      A0A8V0Y0S6, A0A8V0Y9A0
    14. XM_046910497.1XP_046766453.1  focal adhesion kinase 1 isoform X8

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    15. XM_046910506.1XP_046766462.1  focal adhesion kinase 1 isoform X17

      UniProtKB/TrEMBL
      A0A8V0Y0S6, A0A8V0Y4W9
    16. XM_046910505.1XP_046766461.1  focal adhesion kinase 1 isoform X16

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    17. XM_046910503.1XP_046766459.1  focal adhesion kinase 1 isoform X14

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    18. XM_046910501.1XP_046766457.1  focal adhesion kinase 1 isoform X12

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    19. XM_046910504.1XP_046766460.1  focal adhesion kinase 1 isoform X15

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    20. XM_046910502.1XP_046766458.1  focal adhesion kinase 1 isoform X13

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    21. XM_046910500.1XP_046766456.1  focal adhesion kinase 1 isoform X11

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    22. XM_046910499.1XP_046766455.1  focal adhesion kinase 1 isoform X10

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    23. XM_046910496.1XP_046766452.1  focal adhesion kinase 1 isoform X7

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    24. XM_046910491.1XP_046766447.1  focal adhesion kinase 1 isoform X3

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    25. XM_046910494.1XP_046766450.1  focal adhesion kinase 1 isoform X6

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    26. XM_046910492.1XP_046766448.1  focal adhesion kinase 1 isoform X4

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    27. XM_046910490.1XP_046766446.1  focal adhesion kinase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    28. XM_046910489.1XP_046766445.1  focal adhesion kinase 1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y0S6
    29. XM_046910518.1XP_046766474.1  focal adhesion kinase 1 isoform X21

      UniProtKB/TrEMBL
      A0A8V0XWD1
    30. XM_046910509.1XP_046766465.1  focal adhesion kinase 1 isoform X20

      UniProtKB/TrEMBL
      A0A8V0Y0S1
    31. XM_046910498.1XP_046766454.1  focal adhesion kinase 1 isoform X9

      UniProtKB/TrEMBL
      A0A8V0Y0S1
    32. XM_046910521.1XP_046766477.1  focal adhesion kinase 1 isoform X23

    33. XM_046910520.1XP_046766476.1  focal adhesion kinase 1 isoform X22

    34. XM_046910522.1XP_046766478.1  focal adhesion kinase 1 isoform X24

      UniProtKB/TrEMBL
      Q92063

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_205435.1: Suppressed sequence

      Description
      NM_205435.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.