U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    DFNA5 DFNA5, deafness associated tumor suppressor [ Gallus gallus (chicken) ]

    Gene ID: 420623, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Symbol
    DFNA5provided by CGNC
    Full Name
    DFNA5, deafness associated tumor suppressorprovided by CGNC
    Primary source
    CGNC:8357
    See related
    Ensembl:ENSGALG00010002392
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    GSDME
    Orthologs
    human mouse all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See DFNA5 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (31510132..31535014, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (31555447..31586134, complement)

    Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110125 Neighboring gene membrane palmitoylated protein 6 Neighboring gene oxysterol binding protein like 3 Neighboring gene uncharacterized LOC121110126

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in programmed cell death IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    gasdermin-E
    Names
    deafness, autosomal dominant 5
    gasdermin E

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001006361.2 → NP_001006361.2  gasdermin-E

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000037
      UniProtKB/TrEMBL
      A0A8V0XFB5, Q5ZJ76
      Conserved Domains (1) summary
      PRK04778
      Location:289 → 404
      PRK04778; septation ring formation regulator EzrA; Provisional

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      31510132..31535014 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015281448.2 → XP_015136934.2  gasdermin-E isoform X2

      UniProtKB/TrEMBL
      Q5ZJ76
      Conserved Domains (1) summary
      PRK04778
      Location:282 → 397
      PRK04778; septation ring formation regulator EzrA; Provisional

    2. XM_046922914.1 → XP_046778870.1  gasdermin-E isoform X4

      UniProtKB/TrEMBL
      Q5ZJ76

    3. XM_015281445.4 → XP_015136931.2  gasdermin-E isoform X1

      UniProtKB/TrEMBL
      A0A8V0XFB5, Q5ZJ76
      Related
      ENSGALP00010003328.1, ENSGALT00010005489.1
      Conserved Domains (1) summary
      PRK04778
      Location:289 → 404
      PRK04778; septation ring formation regulator EzrA; Provisional

    4. XM_015281446.4 → XP_015136932.2  gasdermin-E isoform X1

      UniProtKB/TrEMBL
      A0A8V0XFB5, Q5ZJ76
      Related
      ENSGALP00010003330.1, ENSGALT00010005491.1
      Conserved Domains (1) summary
      PRK04778
      Location:289 → 404
      PRK04778; septation ring formation regulator EzrA; Provisional

    5. XM_046922876.1 → XP_046778832.1  gasdermin-E isoform X1

      UniProtKB/TrEMBL
      A0A8V0XFB5, Q5ZJ76

    6. XM_046922901.1 → XP_046778857.1  gasdermin-E isoform X1

      UniProtKB/TrEMBL
      A0A8V0XFB5, Q5ZJ76

    7. XM_046922894.1 → XP_046778850.1  gasdermin-E isoform X1

      UniProtKB/TrEMBL
      A0A8V0XFB5, Q5ZJ76

    8. XM_040681790.1 → XP_040537724.1  gasdermin-E isoform X3

      Conserved Domains (1) summary
      PRK04778
      Location:230 → 345
      PRK04778; septation ring formation regulator EzrA; Provisional

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      31555447..31586134 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046911139.1 → XP_046767095.1  gasdermin-E isoform X2

      UniProtKB/TrEMBL
      Q5ZJ76

    2. XM_046911141.1 → XP_046767097.1  gasdermin-E isoform X4

      UniProtKB/TrEMBL
      Q5ZJ76

    3. XM_046911136.1 → XP_046767092.1  gasdermin-E isoform X1

      UniProtKB/TrEMBL
      A0A8V0XFB5, Q5ZJ76

    4. XM_046911137.1 → XP_046767093.1  gasdermin-E isoform X1

      UniProtKB/TrEMBL
      A0A8V0XFB5, Q5ZJ76

    5. XM_046911138.1 → XP_046767094.1  gasdermin-E isoform X1

      UniProtKB/TrEMBL
      A0A8V0XFB5, Q5ZJ76

    6. XM_046911140.1 → XP_046767096.1  gasdermin-E isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials