TTC3 tetratricopeptide repeat domain 3 [Gallus gallus (chicken)] - Gene

Summary

Symbol: TTC3provided by CGNC
Full Name: tetratricopeptide repeat domain 3provided by CGNC
Primary source: CGNC:11990
See related: Ensembl:ENSGALG00010013135
Gene type: protein coding
RefSeq status: MODEL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 48

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	1	NC_052532.1 (107094291..107154237)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	1	NC_052573.1 (107183798..107243747)

Chromosome 1 - NC_052532.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: E3 ubiquitin-protein ligase TTC3

XP_015156894.1

EC 2.3.2.27

XP_015156902.1

EC 2.3.2.27

XP_015156908.1

EC 2.3.2.27

XP_015156915.1

EC 2.3.2.27

XP_015156920.1

EC 2.3.2.27

XP_015156926.2

EC 2.3.2.27

XP_025001034.1

EC 2.3.2.27

XP_040508021.1

EC 2.3.2.27

XP_040515568.1

EC 2.3.2.27

XP_040515569.1

EC 2.3.2.27

XP_040515570.1

EC 2.3.2.27

XP_040515571.1

EC 2.3.2.27

XP_040515572.1

EC 2.3.2.27

XP_040515573.1

EC 2.3.2.27

XP_040515574.1

EC 2.3.2.27

XP_040515576.1

EC 2.3.2.27

XP_040515578.1

EC 2.3.2.27

XP_046761609.1

EC 2.3.2.27

XP_046761611.1

EC 2.3.2.27

XP_046761614.1

EC 2.3.2.27

XP_046761617.1

EC 2.3.2.27

XP_046761620.1

EC 2.3.2.27

XP_046765641.1

EC 2.3.2.27

XP_046765642.1

EC 2.3.2.27

XP_046765643.1

EC 2.3.2.27

XP_046765644.1

EC 2.3.2.27

XP_046765645.1

EC 2.3.2.27

XP_416727.4

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

107094291..107154237

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_416727.8 → XP_416727.4 E3 ubiquitin-protein ligase TTC3 isoform X1

Conserved Domains (4) summary

cd00162
Location:1920 → 1963

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

sd00006
Location:212 → 240

TPR; TPR repeat [structural motif]

pfam12678
Location:1917 → 1960

zf-rbx1; RING-H2 zinc finger

pfam13414
Location:211 → 277

TPR_11; TPR repeat
XM_015301408.4 → XP_015156894.1 E3 ubiquitin-protein ligase TTC3 isoform X2

Conserved Domains (4) summary

cd00162
Location:1919 → 1962

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

sd00006
Location:211 → 239

TPR; TPR repeat [structural motif]

pfam12678
Location:1916 → 1959

zf-rbx1; RING-H2 zinc finger

pfam13414
Location:210 → 276

TPR_11; TPR repeat
XM_046905661.1 → XP_046761617.1 E3 ubiquitin-protein ligase TTC3 isoform X6
XM_046905655.1 → XP_046761611.1 E3 ubiquitin-protein ligase TTC3 isoform X6
XM_015301422.4 → XP_015156908.1 E3 ubiquitin-protein ligase TTC3 isoform X3

UniProtKB/TrEMBL

F1P0T0

Conserved Domains (4) summary

cd00162
Location:1912 → 1955

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

sd00006
Location:204 → 232

TPR; TPR repeat [structural motif]

pfam12678
Location:1909 → 1952

zf-rbx1; RING-H2 zinc finger

pfam13414
Location:203 → 269

TPR_11; TPR repeat
XM_025145266.3 → XP_025001034.1 E3 ubiquitin-protein ligase TTC3 isoform X4

Conserved Domains (5) summary

COG5574
Location:1781 → 1905

PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]

sd00006
Location:149 → 177

TPR; TPR repeat [structural motif]

cd16481
Location:1856 → 1897

RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins

cl25732
Location:1347 → 1602

SMC_N; RecF/RecN/SMC N terminal domain

cl26005
Location:135 → 284

PLN03088; SGT1, suppressor of G2 allele of SKP1; Provisional
XM_015301434.4 → XP_015156920.1 E3 ubiquitin-protein ligase TTC3 isoform X5

UniProtKB/TrEMBL

A0A8V0YQG6

Related

ENSGALP00010018411.1, ENSGALT00010031521.1

Conserved Domains (4) summary

cd00162
Location:1856 → 1899

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

sd00006
Location:148 → 176

TPR; TPR repeat [structural motif]

pfam12678
Location:1853 → 1896

zf-rbx1; RING-H2 zinc finger

pfam13414
Location:147 → 213

TPR_11; TPR repeat
XM_015301416.4 → XP_015156902.1 E3 ubiquitin-protein ligase TTC3 isoform X3

UniProtKB/TrEMBL

F1P0T0

Related

ENSGALP00010018436.1, ENSGALT00010031560.1

Conserved Domains (4) summary

cd00162
Location:1912 → 1955

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

sd00006
Location:204 → 232

TPR; TPR repeat [structural motif]

pfam12678
Location:1909 → 1952

zf-rbx1; RING-H2 zinc finger

pfam13414
Location:203 → 269

TPR_11; TPR repeat
XM_040652087.2 → XP_040508021.1 E3 ubiquitin-protein ligase TTC3 isoform X6

Conserved Domains (6) summary

COG1196
Location:1196 → 1451

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

COG5574
Location:1630 → 1754

PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]

TIGR00990
Location:1 → 133

3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)

sd00006
Location:1 → 26

TPR; TPR repeat [structural motif]

cd16481
Location:1705 → 1746

RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins

pfam19179
Location:396 → 511

DUF5861; Family of unknown function (DUF5861)
XM_046905664.1 → XP_046761620.1 E3 ubiquitin-protein ligase TTC3 isoform X6
XM_046905658.1 → XP_046761614.1 E3 ubiquitin-protein ligase TTC3 isoform X6
XM_015301429.4 → XP_015156915.1 E3 ubiquitin-protein ligase TTC3 isoform X3

UniProtKB/TrEMBL

F1P0T0

Conserved Domains (4) summary

cd00162
Location:1912 → 1955

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

sd00006
Location:204 → 232

TPR; TPR repeat [structural motif]

pfam12678
Location:1909 → 1952

zf-rbx1; RING-H2 zinc finger

pfam13414
Location:203 → 269

TPR_11; TPR repeat
XM_046905653.1 → XP_046761609.1 E3 ubiquitin-protein ligase TTC3 isoform X6
XM_015301440.4 → XP_015156926.2 E3 ubiquitin-protein ligase TTC3 isoform X7

Conserved Domains (3) summary

COG1196
Location:1044 → 1299

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

COG5574
Location:1478 → 1602

PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]

cd16481
Location:1553 → 1594

RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

107183798..107243747

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040659634.2 → XP_040515568.1 E3 ubiquitin-protein ligase TTC3 isoform X1

Conserved Domains (5) summary

COG1196
Location:1410 → 1665

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

COG5574
Location:1844 → 1968

PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]

TIGR00990
Location:198 → 347

3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)

sd00006
Location:212 → 240

TPR; TPR repeat [structural motif]

cd16481
Location:1919 → 1960

RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins
XM_040659635.2 → XP_040515569.1 E3 ubiquitin-protein ligase TTC3 isoform X2

Conserved Domains (5) summary

COG1196
Location:1409 → 1664

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

COG5574
Location:1843 → 1967

PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]

TIGR00990
Location:197 → 346

3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)

sd00006
Location:211 → 239

TPR; TPR repeat [structural motif]

cd16481
Location:1918 → 1959

RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins
XM_046909688.1 → XP_046765644.1 E3 ubiquitin-protein ligase TTC3 isoform X6
XM_046909686.1 → XP_046765642.1 E3 ubiquitin-protein ligase TTC3 isoform X6
XM_040659637.2 → XP_040515571.1 E3 ubiquitin-protein ligase TTC3 isoform X3

Conserved Domains (5) summary

COG1196
Location:1402 → 1657

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

COG5574
Location:1836 → 1960

PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]

TIGR00990
Location:190 → 339

3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)

sd00006
Location:204 → 232

TPR; TPR repeat [structural motif]

cd16481
Location:1911 → 1952

RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins
XM_040659639.2 → XP_040515573.1 E3 ubiquitin-protein ligase TTC3 isoform X4

Conserved Domains (5) summary

COG1196
Location:1347 → 1602

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

COG5574
Location:1781 → 1905

PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]

TIGR00990
Location:135 → 284

3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)

sd00006
Location:149 → 177

TPR; TPR repeat [structural motif]

cd16481
Location:1856 → 1897

RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins
XM_040659640.2 → XP_040515574.1 E3 ubiquitin-protein ligase TTC3 isoform X5

Conserved Domains (5) summary

COG1196
Location:1346 → 1601

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

COG5574
Location:1780 → 1904

PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]

TIGR00990
Location:134 → 283

3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)

sd00006
Location:148 → 176

TPR; TPR repeat [structural motif]

cd16481
Location:1855 → 1896

RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins
XM_040659636.2 → XP_040515570.1 E3 ubiquitin-protein ligase TTC3 isoform X3

Conserved Domains (5) summary

COG1196
Location:1402 → 1657

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

COG5574
Location:1836 → 1960

PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]

TIGR00990
Location:190 → 339

3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)

sd00006
Location:204 → 232

TPR; TPR repeat [structural motif]

cd16481
Location:1911 → 1952

RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins
XM_040659642.2 → XP_040515576.1 E3 ubiquitin-protein ligase TTC3 isoform X6

Conserved Domains (5) summary

COG1196
Location:1196 → 1451

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

COG5574
Location:1630 → 1754

PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]

TIGR00990
Location:1 → 133

3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)

sd00006
Location:1 → 26

TPR; TPR repeat [structural motif]

cd16481
Location:1705 → 1746

RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins
XM_046909689.1 → XP_046765645.1 E3 ubiquitin-protein ligase TTC3 isoform X6
XM_046909687.1 → XP_046765643.1 E3 ubiquitin-protein ligase TTC3 isoform X6
XM_040659638.2 → XP_040515572.1 E3 ubiquitin-protein ligase TTC3 isoform X3

Conserved Domains (5) summary

COG1196
Location:1402 → 1657

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

COG5574
Location:1836 → 1960

PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]

TIGR00990
Location:190 → 339

3a0801s09; mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70)

sd00006
Location:204 → 232

TPR; TPR repeat [structural motif]

cd16481
Location:1911 → 1952

RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins
XM_046909685.1 → XP_046765641.1 E3 ubiquitin-protein ligase TTC3 isoform X6
XM_040659644.2 → XP_040515578.1 E3 ubiquitin-protein ligase TTC3 isoform X7

Conserved Domains (3) summary

COG1196
Location:1044 → 1299

Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

COG5574
Location:1478 → 1602

PEX10; RING-finger-containing E3 ubiquitin ligase [Posttranslational modification, protein turnover, chaperones]

cd16481
Location:1553 → 1594

RING-H2_TTC3; RING finger, H2 subclass, found in Tetratricopeptide repeat protein 3 (TTC3) and similar proteins