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    BRE brain and reproductive organ-expressed (TNFRSF1A modulator) [ Gallus gallus (chicken) ]

    Gene ID: 421417, updated on 3-Dec-2024

    Summary

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    Symbol
    BREprovided by CGNC
    Full Name
    brain and reproductive organ-expressed (TNFRSF1A modulator)provided by CGNC
    Primary source
    CGNC:7632
    See related
    Ensembl:ENSGALG00010021648
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    BABAM2
    Orthologs
    human mouse all
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    Genomic context

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    See BRE in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (27103698..27268596, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (27029688..27194555, complement)

    Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124418348 Neighboring gene translation initiation factor IF-2-like Neighboring gene FOS like 2, AP-1 transcription factor subunit Neighboring gene uncharacterized LOC107052918 Neighboring gene uncharacterized LOC121110340 Neighboring gene ribokinase Neighboring gene mitochondrial ribosomal protein L33

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Misexpression of BRE gene in the developing chick neural tube affects neurulation and somitogenesis. Wang G, et al. Mol Biol Cell, 2015 Mar 1. PMID 25568339, Free PMC Article
    2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Increased or decreased BRE expression affects somitogenesis, neurogenesis, and NCC migration during early chick embryo development.
      Title: Misexpression of BRE gene in the developing chick neural tube affects neurulation and somitogenesis.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in double-strand break repair IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of BRCA1-A complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of BRISC complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    BRISC and BRCA1-A complex member 2
    Names
    BRCA1-A complex subunit BRE
    BRCA1/BRCA2-containing complex subunit 45
    BRISC and BRCA1 A complex member 2
    brain and reproductive organ-expressed protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001008458.2 → NP_001008458.1  BRISC and BRCA1-A complex member 2

      See identical proteins and their annotated locations for NP_001008458.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000063
      UniProtKB/Swiss-Prot
      Q5ZML0
      UniProtKB/TrEMBL
      A0A8V0ZJG8
      Related
      ENSGALP00010031508.1, ENSGALT00010052602.1
      Conserved Domains (1) summary
      pfam06113
      Location:8 → 333
      BRE; Brain and reproductive organ-expressed protein (BRE)

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      27103698..27268596 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015283708.4 → XP_015139194.1  BRISC and BRCA1-A complex member 2 isoform X1

      UniProtKB/Swiss-Prot
      Q5ZML0
      UniProtKB/TrEMBL
      A0A8V0ZJG8
      Conserved Domains (1) summary
      pfam06113
      Location:8 → 333
      BRE; Brain and reproductive organ-expressed protein (BRE)

    2. XM_046938812.1 → XP_046794768.1  BRISC and BRCA1-A complex member 2 isoform X1

      UniProtKB/Swiss-Prot
      Q5ZML0
      UniProtKB/TrEMBL
      A0A8V0ZJG8

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      27029688..27194555 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046913811.1 → XP_046769767.1  BRISC and BRCA1-A complex member 2 isoform X1

      UniProtKB/Swiss-Prot
      Q5ZML0
      UniProtKB/TrEMBL
      A0A8V0ZJG8

    2. XM_046913812.1 → XP_046769768.1  BRISC and BRCA1-A complex member 2 isoform X1

      UniProtKB/Swiss-Prot
      Q5ZML0
      UniProtKB/TrEMBL
      A0A8V0ZJG8
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5ZML0.1 GenPept UniProtKB/Swiss-Prot:Q5ZML0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.