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    DENND2A DENN domain containing 2A [ Gallus gallus (chicken) ]

    Gene ID: 418115, updated on 3-Dec-2024

    Summary

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    Official Symbol
    DENND2Aprovided by CGNC
    Official Full Name
    DENN domain containing 2Aprovided by CGNC
    Primary source
    CGNC:9739
    See related
    Ensembl:ENSGALG00010013381
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Orthologs
    human mouse all
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    Genomic context

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    See DENND2A in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (56877489..56934909, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (57178373..57235784, complement)

    Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene pseudouridine-5'-phosphate glycosidase-like Neighboring gene uncharacterized LOC121106531 Neighboring gene aarF domain containing kinase 2 Neighboring gene trichohyalin-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Process Evidence Code Pubs
    involved_in retrograde transport, endosome to Golgi IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    DENN domain-containing protein 2A
    Names
    DENN/MADD domain containing 2A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      56877489..56934909 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025156009.3 → XP_025011777.1  DENN domain-containing protein 2A isoform X3

      UniProtKB/TrEMBL
      A0A8V0YJL6, A0A8V0YJM1
      Related
      ENSGALP00010019010.1, ENSGALT00010032220.1
      Conserved Domains (3) summary
      smart00801
      Location:1001 → 1067
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:668 → 760
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:767 → 939
      DENN; DENN (AEX-3) domain

    2. XM_025156008.3 → XP_025011776.1  DENN domain-containing protein 2A isoform X1

      UniProtKB/TrEMBL
      A0A8V0YJL6
      Conserved Domains (3) summary
      smart00801
      Location:1006 → 1072
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:668 → 765
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:772 → 944
      DENN; DENN (AEX-3) domain

    3. XM_040658943.2 → XP_040514877.1  DENN domain-containing protein 2A isoform X6

      UniProtKB/TrEMBL
      A0A8V0YJL6
      Related
      ENSGALP00010019005.1, ENSGALT00010032215.1
      Conserved Domains (3) summary
      smart00801
      Location:989 → 1055
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:756 → 927
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:656 → 748
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    4. XM_004937866.5 → XP_004937923.2  DENN domain-containing protein 2A isoform X5

      UniProtKB/TrEMBL
      A0A8V0YJL6, A0A8V0YK97
      Related
      ENSGALP00010019008.1, ENSGALT00010032218.1
      Conserved Domains (3) summary
      smart00801
      Location:994 → 1060
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:656 → 753
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:760 → 932
      DENN; DENN (AEX-3) domain

    5. XM_040658950.2 → XP_040514884.1  DENN domain-containing protein 2A isoform X6

      UniProtKB/TrEMBL
      A0A8V0YJL6
      Conserved Domains (3) summary
      smart00801
      Location:989 → 1055
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:756 → 927
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:656 → 748
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    6. XM_046910117.1 → XP_046766073.1  DENN domain-containing protein 2A isoform X5

      UniProtKB/TrEMBL
      A0A8V0YJL6, A0A8V0YK97

    7. XM_025156010.3 → XP_025011778.1  DENN domain-containing protein 2A isoform X5

      UniProtKB/TrEMBL
      A0A8V0YJL6, A0A8V0YK97
      Conserved Domains (3) summary
      smart00801
      Location:994 → 1060
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:656 → 753
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:760 → 932
      DENN; DENN (AEX-3) domain

    8. XM_040658918.2 → XP_040514852.1  DENN domain-containing protein 2A isoform X4

      UniProtKB/TrEMBL
      A0A8V0YJL6
      Conserved Domains (3) summary
      smart00801
      Location:1006 → 1072
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:773 → 944
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:668 → 765
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    9. XM_040658905.2 → XP_040514839.1  DENN domain-containing protein 2A isoform X2

      UniProtKB/TrEMBL
      A0A8V0YJL6
      Conserved Domains (3) summary
      smart00801
      Location:1006 → 1072
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:773 → 944
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:668 → 765
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    10. XM_025156011.3 → XP_025011779.2  DENN domain-containing protein 2A isoform X7

      UniProtKB/TrEMBL
      A0A8V0YJL6
      Conserved Domains (2) summary
      smart00799
      Location:773 → 944
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:668 → 765
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      57178373..57235784 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040660865.2 → XP_040516799.1  DENN domain-containing protein 2A isoform X3

      UniProtKB/TrEMBL
      A0A8V0YJL6, A0A8V0YJM1
      Conserved Domains (3) summary
      smart00801
      Location:1001 → 1067
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:668 → 760
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:767 → 939
      DENN; DENN (AEX-3) domain

    2. XM_040660863.2 → XP_040516797.1  DENN domain-containing protein 2A isoform X1

      UniProtKB/TrEMBL
      A0A8V0YJL6
      Conserved Domains (3) summary
      smart00801
      Location:1006 → 1072
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:668 → 765
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:772 → 944
      DENN; DENN (AEX-3) domain

    3. XM_040660869.2 → XP_040516803.1  DENN domain-containing protein 2A isoform X6

      UniProtKB/TrEMBL
      A0A8V0YJL6
      Conserved Domains (3) summary
      smart00801
      Location:989 → 1055
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:756 → 927
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:656 → 748
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    4. XM_040660867.2 → XP_040516801.1  DENN domain-containing protein 2A isoform X5

      UniProtKB/TrEMBL
      A0A8V0YJL6, A0A8V0YK97
      Conserved Domains (3) summary
      smart00801
      Location:994 → 1060
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:656 → 753
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:760 → 932
      DENN; DENN (AEX-3) domain

    5. XM_040660870.2 → XP_040516804.1  DENN domain-containing protein 2A isoform X6

      UniProtKB/TrEMBL
      A0A8V0YJL6
      Conserved Domains (3) summary
      smart00801
      Location:989 → 1055
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:756 → 927
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:656 → 748
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    6. XM_046908936.1 → XP_046764892.1  DENN domain-containing protein 2A isoform X5

      UniProtKB/TrEMBL
      A0A8V0YJL6, A0A8V0YK97

    7. XM_040660868.2 → XP_040516802.1  DENN domain-containing protein 2A isoform X5

      UniProtKB/TrEMBL
      A0A8V0YJL6, A0A8V0YK97
      Conserved Domains (3) summary
      smart00801
      Location:994 → 1060
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00800
      Location:656 → 753
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
      pfam02141
      Location:760 → 932
      DENN; DENN (AEX-3) domain

    8. XM_040660866.2 → XP_040516800.1  DENN domain-containing protein 2A isoform X4

      UniProtKB/TrEMBL
      A0A8V0YJL6
      Conserved Domains (3) summary
      smart00801
      Location:1006 → 1072
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:773 → 944
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:668 → 765
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    9. XM_040660864.2 → XP_040516798.1  DENN domain-containing protein 2A isoform X2

      UniProtKB/TrEMBL
      A0A8V0YJL6
      Conserved Domains (3) summary
      smart00801
      Location:1006 → 1072
      dDENN; Domain always found downstream of DENN domain, found in a variety of signalling proteins
      smart00799
      Location:773 → 944
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:668 → 765
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins

    10. XM_040660871.2 → XP_040516805.1  DENN domain-containing protein 2A isoform X7

      UniProtKB/TrEMBL
      A0A8V0YJL6
      Conserved Domains (2) summary
      smart00799
      Location:773 → 944
      DENN; Domain found in a variety of signalling proteins, always encircled by uDENN and dDENN
      smart00800
      Location:668 → 765
      uDENN; Domain always found upstream of DENN domain, found in a variety of signalling proteins
    Nucleotide Protein
    Heading Accession and Version

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