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    Tasor2 transcription activation suppressor family member 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 361269, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tasor2provided by RGD
    Official Full Name
    transcription activation suppressor family member 2provided by RGD
    Primary source
    RGD:1564456
    See related
    EnsemblRapid:ENSRNOG00000018011 AllianceGenome:RGD:1564456
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fam208b; RGD1564456
    Summary
    Predicted to be involved in negative regulation of gene expression, epigenetic. Predicted to be located in cytosol. Predicted to be active in nucleoplasm. Orthologous to human TASOR2 (transcription activation suppressor family member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Testes (RPKM 239.3), Thymus (RPKM 145.4) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Tasor2 in Genome Data Viewer
    Location:
    17q12.2
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 17 NC_086035.1 (71504656..71559878)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 17 NC_051352.1 (66583554..66650127)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 17 NC_005116.4 (70245672..70299056)

    Chromosome 17 - NC_086035.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L29, pseudogene 3 Neighboring gene ankyrin repeat and SOCS box-containing 13 Neighboring gene uncharacterized LOC134482597 Neighboring gene GDP dissociation inhibitor 2 Neighboring gene uncharacterized LOC120097798 Neighboring gene uncharacterized LOC120097902

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in negative regulation of gene expression, epigenetic IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    protein TASOR 2
    Names
    family with sequence similarity 208, member B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001427686.2 → NP_001414615.1  protein TASOR 2

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000017
      UniProtKB/TrEMBL
      A0A8I5ZTH0, D3ZVI2
      Related
      ENSRNOP00000051465.6, ENSRNOT00000048933.8

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086035.1 Reference GRCr8

      Range
      71504656..71559878
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006254223.5 → XP_006254285.1  protein TASOR 2 isoform X2

      See identical proteins and their annotated locations for XP_006254285.1

      UniProtKB/TrEMBL
      A0A8I5ZTH0
      Conserved Domains (2) summary
      pfam12480
      Location:94 → 167
      DUF3699; Protein of unknown function (DUF3699)
      pfam12509
      Location:552 → 704
      DUF3715; Protein of unknown function (DUF3715)

    2. XM_039096362.2 → XP_038952290.1  protein TASOR 2 isoform X4

      Conserved Domains (2) summary
      pfam12480
      Location:94 → 167
      DUF3699; Protein of unknown function (DUF3699)
      pfam12509
      Location:552 → 704
      DUF3715; Protein of unknown function (DUF3715)

    3. XM_039096361.2 → XP_038952289.1  protein TASOR 2 isoform X3

      UniProtKB/TrEMBL
      A0A8I5ZTH0
      Conserved Domains (2) summary
      pfam12480
      Location:94 → 167
      DUF3699; Protein of unknown function (DUF3699)
      pfam12509
      Location:552 → 704
      DUF3715; Protein of unknown function (DUF3715)

    4. XM_006254222.5 → XP_006254284.1  protein TASOR 2 isoform X1

      See identical proteins and their annotated locations for XP_006254284.1

      UniProtKB/TrEMBL
      A0A8I5ZTH0, D3ZVI2
      Conserved Domains (2) summary
      pfam12480
      Location:94 → 167
      DUF3699; Protein of unknown function (DUF3699)
      pfam12509
      Location:552 → 704
      DUF3715; Protein of unknown function (DUF3715)

    5. XM_006254224.5 → XP_006254286.1  protein TASOR 2 isoform X2

      See identical proteins and their annotated locations for XP_006254286.1

      UniProtKB/TrEMBL
      A0A8I5ZTH0
      Conserved Domains (2) summary
      pfam12480
      Location:94 → 167
      DUF3699; Protein of unknown function (DUF3699)
      pfam12509
      Location:552 → 704
      DUF3715; Protein of unknown function (DUF3715)

    6. XM_006254221.5 → XP_006254283.1  protein TASOR 2 isoform X1

      See identical proteins and their annotated locations for XP_006254283.1

      UniProtKB/TrEMBL
      A0A8I5ZTH0, D3ZVI2
      Conserved Domains (2) summary
      pfam12480
      Location:94 → 167
      DUF3699; Protein of unknown function (DUF3699)
      pfam12509
      Location:552 → 704
      DUF3715; Protein of unknown function (DUF3715)
    Nucleotide Protein Strain
    Heading Accession and Version

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