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    Lrrc58 leucine rich repeat containing 58 [ Mus musculus (house mouse) ]

    Gene ID: 320184, updated on 9-Dec-2024

    Summary

    Official Symbol
    Lrrc58provided by MGI
    Official Full Name
    leucine rich repeat containing 58provided by MGI
    Primary source
    MGI:MGI:2443542
    See related
    Ensembl:ENSMUSG00000034158 AllianceGenome:MGI:2443542
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1810012N18Rik; C330018J07Rik
    Summary
    Predicted to be involved in intracellular signal transduction. Orthologous to human LRRC58 (leucine rich repeat containing 58). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in ovary adult (RPKM 37.6), subcutaneous fat pad adult (RPKM 32.2) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Lrrc58 in Genome Data Viewer
    Location:
    16 B3; 16 26.49 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (37688762..37709219)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (37868400..37888857)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene follistatin-like 1 Neighboring gene STARR-seq mESC enhancer starr_40798 Neighboring gene predicted gene, 41452 Neighboring gene butyrophilin-like 12 Neighboring gene VISTA enhancer mm1361 Neighboring gene actin, beta, cytoplasmic (Actb) pseudogene Neighboring gene STARR-seq mESC enhancer starr_40799 Neighboring gene G protein-coupled receptor 156 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:37963429-37963630 Neighboring gene predicted gene, 36225 Neighboring gene predicted gene, 25140 Neighboring gene STARR-seq mESC enhancer starr_40800 Neighboring gene RIKEN cDNA 4930542C21 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    leucine-rich repeat-containing protein 58

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177093.3NP_796067.2  leucine-rich repeat-containing protein 58

      See identical proteins and their annotated locations for NP_796067.2

      Status: VALIDATED

      Source sequence(s)
      AC161268, AK049274
      Consensus CDS
      CCDS37340.1
      UniProtKB/Swiss-Prot
      B2RU81, Q3UGP9, Q8BX06
      Related
      ENSMUSP00000077779.7, ENSMUST00000078717.7
      Conserved Domains (3) summary
      cd00116
      Location:54206
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:6587
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:161219
      LRR_8; Leucine rich repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      37688762..37709219
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)