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    Gpr156 G protein-coupled receptor 156 [ Mus musculus (house mouse) ]

    Gene ID: 239845, updated on 9-Dec-2024

    Summary

    Official Symbol
    Gpr156provided by MGI
    Official Full Name
    G protein-coupled receptor 156provided by MGI
    Primary source
    MGI:MGI:2653880
    See related
    Ensembl:ENSMUSG00000046961 AllianceGenome:MGI:2653880
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gababl
    Summary
    Predicted to enable G protein-coupled GABA receptor activity. Involved in stereocilium bundle organization. Located in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; mammary gland; and trachea. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness. Orthologous to human GPR156 (G protein-coupled receptor 156). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in CNS E14 (RPKM 1.9), whole brain E14.5 (RPKM 1.9) and 13 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Gpr156 in Genome Data Viewer
    Location:
    16 B3; 16 26.54 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (37736551..37827892)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (37916185..38007530)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene butyrophilin-like 12 Neighboring gene VISTA enhancer mm1361 Neighboring gene leucine rich repeat containing 58 Neighboring gene actin, beta, cytoplasmic (Actb) pseudogene Neighboring gene STARR-seq mESC enhancer starr_40799 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:37963429-37963630 Neighboring gene STARR-seq mESC enhancer starr_40800 Neighboring gene predicted gene, 36225 Neighboring gene predicted gene, 25140 Neighboring gene RIKEN cDNA 4930542C21 gene Neighboring gene STARR-positive B cell enhancer mm9_chr16:38088912-38089213 Neighboring gene cDNA sequence BC031361 Neighboring gene glycogen synthase kinase 3 beta

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (3) 

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled GABA receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables G protein-coupled GABA receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in gamma-aminobutyric acid signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in stereocilium bundle organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of G protein-coupled receptor heterodimeric complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    probable G-protein coupled receptor 156
    Names
    GABAB-related G-protein coupled receptor

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153394.2NP_700443.2  probable G-protein coupled receptor 156

      See identical proteins and their annotated locations for NP_700443.2

      Status: PROVISIONAL

      Source sequence(s)
      BC059227
      Consensus CDS
      CCDS28162.1
      UniProtKB/Swiss-Prot
      Q6PCP7, Q8K452
      UniProtKB/TrEMBL
      A0A0R4J0P3
      Related
      ENSMUSP00000055958.8, ENSMUST00000061274.9
      Conserved Domains (2) summary
      TIGR00599
      Location:347538
      rad18; DNA repair protein rad18
      pfam00003
      Location:71141
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      37736551..37827892
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011245894.4XP_011244196.1  probable G-protein coupled receptor 156 isoform X2

      Conserved Domains (2) summary
      cd14964
      Location:4873
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:48315
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    2. XM_006522126.1XP_006522189.1  probable G-protein coupled receptor 156 isoform X1

      Conserved Domains (3) summary
      TIGR00599
      Location:87278
      rad18; DNA repair protein rad18
      cd14964
      Location:2651
      7tm_GPCRs; TM helix 7 [structural motif]
      cl28897
      Location:157
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily