U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Bpifc BPI fold containing family C [ Mus musculus (house mouse) ]

    Gene ID: 270757, updated on 27-Nov-2024

    Summary

    Official Symbol
    Bpifcprovided by MGI
    Official Full Name
    BPI fold containing family Cprovided by MGI
    Primary source
    MGI:MGI:3026884
    See related
    Ensembl:ENSMUSG00000050108 AllianceGenome:MGI:3026884
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Bpil2; 4732454E24
    Summary
    Predicted to enable lipid binding activity. Predicted to be involved in innate immune response. Predicted to be active in extracellular space. Orthologous to human BPIFC (BPI fold containing family C). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in stomach adult (RPKM 1.7), limb E14.5 (RPKM 1.0) and 6 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Bpifc in Genome Data Viewer
    Location:
    10 C1; 10 41.83 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (85795555..85847724, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (85959691..86011860, complement)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

    Markers

    Clone Names

    • MGC130596

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in innate immune response IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    BPI fold-containing family C protein
    Names
    bactericidal/permeability-increasing protein-like 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177772.4NP_808440.2  BPI fold-containing family C protein precursor

      See identical proteins and their annotated locations for NP_808440.2

      Status: VALIDATED

      Source sequence(s)
      AK028764, BB527461, BC112376, BY142313
      Consensus CDS
      CCDS48658.1
      UniProtKB/Swiss-Prot
      Q8C186
      UniProtKB/TrEMBL
      Q3V1D7
      Related
      ENSMUSP00000063107.6, ENSMUST00000061699.12
      Conserved Domains (2) summary
      pfam01273
      Location:38202
      LBP_BPI_CETP; LBP / BPI / CETP family, N-terminal domain
      cl00188
      Location:242478
      BPI; BPI/LBP/CETP domain; Bactericidal permeability-increasing protein (BPI) / Lipopolysaccharide-binding protein (LBP) / Cholesteryl ester transfer protein (CETP) domain; binds to and neutralizes lipopolysaccharides from the outer membrane of Gram-negative ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      85795555..85847724 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)