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    SPPL4 SIGNAL PEPTIDE PEPTIDASE-LIKE 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 839499, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SPPL4
    Official Full Name
    SIGNAL PEPTIDE PEPTIDASE-LIKE 4
    Primary source
    TAIR:AT1G01650
    Locus tag
    AT1G01650
    See related
    Araport:AT1G01650
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA SIGNAL PEPTIDE PEPTIDASE-LIKE 4; ATSPPL4; SIGNAL PEPTIDE PEPTIDASE-LIKE 4; T1N6.3; T1N6_3
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    Genomic context

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    See SPPL4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    14
    Sequence:
    Chromosome: 1; NC_003070.9 (232840..237905, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene plasma membrane intrinsic protein 1C Neighboring gene Sec14p-like phosphatidylinositol transfer family protein Neighboring gene BTB/POZ domain-containing protein Neighboring gene miscRNA Neighboring gene RING/U-box superfamily protein Neighboring gene RING/U-box superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A mesoscale abscisic acid hormone interactome reveals a dynamic signaling landscape in Arabidopsis. Lumba S, et al. Dev Cell, 2014 May 12. PMID 24823379
    2. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001035853.1
    NM_001331286.1
    NM_001331287.1
    NM_100047.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables aspartic endopeptidase activity, intramembrane cleaving IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    SIGNAL PEPTIDE PEPTIDASE-LIKE 4
    NP_001318903.1
    • SIGNAL PEPTIDE PEPTIDASE-LIKE 4 (SPPL4); FUNCTIONS IN: peptidase activity, aspartic-type endopeptidase activity; INVOLVED IN: proteolysis; LOCATED IN: integral to membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase A22, presenilin signal peptide (InterPro:IPR006639), Peptidase A22B, signal peptide peptidase (InterPro:IPR007369); BEST Arabidopsis thaliana protein match is: SIGNAL PEPTIDE PEPTIDASE-LIKE 2 (TAIR:AT1G63690.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_171671.2
    • SIGNAL PEPTIDE PEPTIDASE-LIKE 4 (SPPL4); FUNCTIONS IN: peptidase activity, aspartic-type endopeptidase activity; INVOLVED IN: proteolysis; LOCATED IN: endomembrane system, integral to membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protease-associated PA (InterPro:IPR003137), Peptidase A22, presenilin signal peptide (InterPro:IPR006639), Peptidase A22B, signal peptide peptidase (InterPro:IPR007369); BEST Arabidopsis thaliana protein match is: SIGNAL PEPTIDE PEPTIDASE-LIKE 2 (TAIR:AT1G63690.1); Has 1466 Blast hits to 1433 proteins in 284 species: Archae - 0; Bacteria - 176; Metazoa - 611; Fungi - 153; Plants - 303; Viruses - 0; Other Eukaryotes - 223 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      232840..237905 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100047.4 → NP_171671.2  SIGNAL PEPTIDE PEPTIDASE-LIKE 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WMJ8, Q9LQ94
      UniProtKB/TrEMBL
      A0A178WKW5, A0A178WMP2, A0A5S9S329
      Conserved Domains (2) summary
      pfam04258
      Location:241 → 527
      Peptidase_A22B; Signal peptide peptidase
      cl28883
      Location:46 → 183
      PA; Protease-associated (PA) domain. The PA domain is an insert domain in a diverse fraction of proteases. The significance of the PA domain to many of the proteins in which it is inserted is undetermined. It may be a protein-protein interaction domain. At ...

    2. NM_001035853.1 → NP_001030930.1  SIGNAL PEPTIDE PEPTIDASE-LIKE 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4HU44
      Conserved Domains (2) summary
      pfam04258
      Location:99 → 385
      Peptidase_A22B; Signal peptide peptidase
      cl10459
      Location:1 → 41
      Peptidases_S8_S53; Peptidase domain in the S8 and S53 families

    3. NM_001331286.1 → NP_001318903.1  SIGNAL PEPTIDE PEPTIDASE-LIKE 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4HU44

    4. NM_001331287.1 → NP_001323100.1  SIGNAL PEPTIDE PEPTIDASE-LIKE 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4HU44
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0WMJ8.1

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