Nipsnap1 nipsnap homolog 1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Nipsnap1provided by RGD
Official Full Name: nipsnap homolog 1provided by RGD
Primary source: RGD:1310419
See related: EnsemblRapid:ENSRNOG00000008374 AllianceGenome:RGD:1310419
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in mitophagy and sensory perception of pain. Predicted to be located in membrane. Predicted to be active in mitochondrial matrix and synaptic membrane. Orthologous to human NIPSNAP1 (nipsnap homolog 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in Kidney (RPKM 653.5), Liver (RPKM 605.4) and 6 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 14q21

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	14	NC_086032.1 (83957714..83981579)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	14	NC_051349.1 (79734234..79758101)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	14	NC_005113.4 (85113578..85137457)

Chromosome 14 - NC_086032.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data provide the first experimental evidence for a strictly neuronal expression of NIPSNAP1 in the rat nervous system.
Title: Neuronal localization of the mitochondrial protein NIPSNAP1 in rat nervous system.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

D14Got70 (e-PCR)
- UniSTS:114191

D14Got69 (e-PCR)
- UniSTS:114582

BE119843 (e-PCR)
- UniSTS:249280

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables protein-macromolecule adaptor activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in mitophagy	ISO Inferred from Sequence Orthology more info
involved_in sensory perception of pain	IBA Inferred from Biological aspect of Ancestor more info
involved_in sensory perception of pain	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in membrane	ISO Inferred from Sequence Orthology more info
is_active_in mitochondrial matrix	ISO Inferred from Sequence Orthology more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info
is_active_in synaptic membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: protein NipSnap homolog 1

Names: 4-nitrophenylphosphatase domain and non-neuronal SNAP25-like protein homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.