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    Map7d2 MAP7 domain containing 2 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 317508, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Map7d2provided by RGD
    Official Full Name
    MAP7 domain containing 2provided by RGD
    Primary source
    RGD:1564852
    See related
    EnsemblRapid:ENSRNOG00000005176 AllianceGenome:RGD:1564852
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Brelin; Mtap7d2; RGD1564852
    Summary
    Predicted to be involved in microtubule cytoskeleton organization. Predicted to be active in microtubule cytoskeleton. Orthologous to human MAP7D2 (MAP7 domain containing 2). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Brain (RPKM 176.1), Testes (RPKM 77.4) and 3 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Map7d2 in Genome Data Viewer
    Location:
    Xq14
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) X NC_086039.1 (39181091..39296814, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) X NC_051356.1 (35372453..35488073, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) X NC_005120.4 (38400578..38467825, complement)

    Chromosome X - NC_086039.1Genomic Context describing neighboring genes Neighboring gene BCLAF1 and THRAP3 family member 3 Neighboring gene ribosomal protein S9, pseudogene 13 Neighboring gene eukaryotic translation initiation factor 1A, X-linked Neighboring gene ribosomal protein S6 kinase A3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Interactome analysis of AMP-activated protein kinase (AMPK)-α1 and -β1 in INS-1 pancreatic beta-cells by affinity purification-mass spectrometry. Moon S, et al. Sci Rep, 2014 Mar 14. PMID 24625528, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in microtubule cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    MAP7 domain-containing protein 2
    Names
    brain-enriched E-MAP-115-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001289778.2 → NP_001276707.1  MAP7 domain-containing protein 2

      See identical proteins and their annotated locations for NP_001276707.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000021
      UniProtKB/TrEMBL
      D4A4L4, W0T3G7
      Related
      ENSRNOP00000042347.6, ENSRNOT00000045285.8
      Conserved Domains (2) summary
      pfam17380
      Location:57 → 150
      DUF5401; Family of unknown function (DUF5401)
      pfam05672
      Location:415 → 588
      MAP7; MAP7 (E-MAP-115) family

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086039.1 Reference GRCr8

      Range
      39181091..39296814 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039099843.2 → XP_038955771.1  MAP7 domain-containing protein 2 isoform X2

      UniProtKB/TrEMBL
      A0A8I5ZJE8, A6IPN0
      Related
      ENSRNOP00000077197.1, ENSRNOT00000108099.2
      Conserved Domains (2) summary
      pfam17380
      Location:57 → 150
      DUF5401; Family of unknown function (DUF5401)
      pfam05672
      Location:382 → 555
      MAP7; MAP7 (E-MAP-115) family

    2. XM_039099844.2 → XP_038955772.1  MAP7 domain-containing protein 2 isoform X3

      Conserved Domains (2) summary
      pfam17380
      Location:57 → 150
      DUF5401; Family of unknown function (DUF5401)
      pfam05672
      Location:382 → 543
      MAP7; MAP7 (E-MAP-115) family

    3. XM_039099842.2 → XP_038955770.1  MAP7 domain-containing protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A8I6A4J6
      Related
      ENSRNOP00000086855.1, ENSRNOT00000110899.2
      Conserved Domains (2) summary
      pfam17380
      Location:57 → 150
      DUF5401; Family of unknown function (DUF5401)
      pfam05672
      Location:415 → 576
      MAP7; MAP7 (E-MAP-115) family
    Nucleotide Protein Strain
    Heading Accession and Version

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