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    ril-2 RNAi-Induced Longevity [ Caenorhabditis elegans ]

    Gene ID: 179725, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ril-2
    Official Full Name
    RNAi-Induced Longevity
    Primary source
    WormBase:WBGene00007586
    Locus tag
    CELE_C14C10.3
    See related
    AllianceGenome:WB:WBGene00007586
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in lysosome organization and regulation of intracellular pH. Predicted to be located in membrane. Predicted to be active in lysosome. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ril-2 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    7
    Sequence:
    Chromosome: V; NC_003283.11 (12596387..12599157, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ERAP1_C domain-containing protein Neighboring gene Leucine-rich PPR motif-containing protein, mitochondrial Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Proteasome activator complex subunit 4 Neighboring gene ncRNA Neighboring gene putative ergosterol biosynthetic protein 28 homolog Neighboring gene Conserved secreted protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. New genes tied to endocrine, metabolic, and dietary regulation of lifespan from a Caenorhabditis elegans genomic RNAi screen. Hansen M, et al. PLoS Genet, 2005 Jul. PMID 16103914, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in lysosome organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of intracellular pH IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in lysosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    RNAi-Induced Longevity
    NP_001023658.1
    • Product from WormBase gene class ril;
      Confirmed by transcript evidence
    NP_001023659.1
    • Product from WormBase gene class ril;
      Confirmed by transcript evidence
    NP_001256436.1
    • Product from WormBase gene class ril;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      12596387..12599157 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001028488.6 → NP_001023659.1  RNAi-Induced Longevity [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001023659.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q52GY7

    2. NM_001269507.4 → NP_001256436.1  RNAi-Induced Longevity [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256436.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E3W740

    3. NM_001028487.8 → NP_001023658.1  RNAi-Induced Longevity [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001023658.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17973
    Nucleotide Protein
    Heading Accession and Version

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