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    cyp-33C5 CYtochrome P450 family [ Caenorhabditis elegans ]

    Gene ID: 178706, updated on 9-Dec-2024

    Summary

    Official Symbol
    cyp-33C5
    Official Full Name
    CYtochrome P450 family
    Primary source
    WormBase:WBGene00018261
    Locus tag
    CELE_F41B5.3
    See related
    AllianceGenome:WB:WBGene00018261
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Human ortholog(s) of this gene implicated in end stage renal disease and renal hypertension. Orthologous to human CYP2C8 (cytochrome P450 family 2 subfamily C member 8). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See cyp-33C5 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (2245004..2247029)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene CYtochrome P450 family Neighboring gene CYtochrome P450 family Neighboring gene CYtochrome P450 family

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in organic acid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in xenobiotic metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    CYtochrome P450 family
    NP_001300106.1
    • Confirmed by transcript evidence
    NP_503616.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      2245004..2247029
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071215.4NP_503616.1  CYtochrome P450 family [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_503616.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O16671
      Conserved Domains (1) summary
      pfam00067
      Location:26483
      p450; Cytochrome P450
    2. NM_001313177.3NP_001300106.1  CYtochrome P450 family [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AUW1
      Conserved Domains (1) summary
      pfam00067
      Location:2377
      p450; Cytochrome P450