arv-1 Protein ARV [Caenorhabditis elegans] - Gene

Summary

Official Symbol: arv-1
Official Full Name: Protein ARV
Primary source: WormBase:WBGene00011040
Locus tag: CELE_R05H5.5
See related: AllianceGenome:WB:WBGene00011040
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in several processes, including intracellular sterol transport; regulation of plasma membrane sterol distribution; and sterol metabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in Golgi apparatus and cortical endoplasmic reticulum. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 38. Orthologous to human ARV1 (ARV1 homolog, fatty acid homeostasis modulator). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome II - NC_003280.10 Genomic Context describing neighboring genes

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Process	Evidence Code	Pubs
involved_in intracellular sterol transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular sterol transport	IEA Inferred from Electronic Annotation more info
involved_in lipid metabolic process	IEA Inferred from Electronic Annotation more info
involved_in lipid transport	IEA Inferred from Electronic Annotation more info
involved_in regulation of plasma membrane sterol distribution	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of plasma membrane sterol distribution	IEA Inferred from Electronic Annotation more info
involved_in sphingolipid metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in sterol metabolic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in sterol metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in Golgi apparatus	IBA Inferred from Biological aspect of Ancestor more info
is_active_in cortical endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

NP_001369870.1

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The following sections contain reference sequences that belong to a specific genome build. Explain