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    F47B8.4 Glutaredoxin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179930, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F47B8.4
    Official Full Name
    Glutaredoxin domain-containing protein
    Primary source
    WormBase:WBGene00009805
    Locus tag
    CELE_F47B8.4
    See related
    AllianceGenome:WB:WBGene00009805
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in innate immune response. Predicted to be active in mitochondrial matrix. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F47B8.4 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    4
    Sequence:
    Chromosome: V; NC_003283.11 (14323528..14324673, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Skin secretory protein xP2-like Neighboring gene Glutaredoxin domain-containing protein Neighboring gene Skin secretory protein xP2-like Neighboring gene ncRNA Neighboring gene Methyltransferase FkbM domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Shapira M, et al. Proc Natl Acad Sci U S A, 2006 Sep 19. PMID 16968778, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in innate immune response HEP PubMed 
    Component Evidence Code Pubs
    is_active_in mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Glutaredoxin domain-containing protein
    NP_001256578.1
    • Confirmed by transcript evidence
    NP_001256579.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      14323528..14324673 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001269650.2 → NP_001256579.1  Glutaredoxin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256579.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20518
      Conserved Domains (1) summary
      cl00388
      Location:185 → 228
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold

    2. NM_001269649.4 → NP_001256578.1  Glutaredoxin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256578.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2FLI1
      Conserved Domains (1) summary
      cl00388
      Location:219 → 262
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
    Nucleotide Protein
    Heading Accession and Version

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