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    ldp-1 Lipid droplet localized protein [ Caenorhabditis elegans ]

    Gene ID: 178692, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ldp-1
    Official Full Name
    Lipid droplet localized protein
    Primary source
    WormBase:WBGene00017719
    Locus tag
    CELE_F22F7.1
    See related
    AllianceGenome:WB:WBGene00017719
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in glycolipid biosynthetic process. Predicted to be located in membrane. Predicted to be active in lipid droplet. Is expressed in several structures, including body wall musculature; intestine; nervous system; pharynx; and tail. Orthologous to human SCCPDH (saccharopine dehydrogenase (putative)). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ldp-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (2127535..2130100)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Saccharopine dehydrogenase NADP binding domain-containing protein Neighboring gene Gamma-glutamylcyclotransferase;glutathione-specific gamma-glutamylcyclotransferase Neighboring gene Seven TM Receptor

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Spatial single-cell sequencing of meiosis I arrested oocytes indicates acquisition of maternal transcripts from the soma. Trimmer KA, et al. Cell Rep, 2023 Jun 27. PMID 37227820, Free PMC Article
    2. CCAR-1 works together with the U2AF large subunit UAF-1 to regulate alternative splicing. Lugano DI, et al. RNA Biol, 2024 Jan. PMID 38126797, Free PMC Article
    3. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in glycolipid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in lipid droplet IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in lipid droplet IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Lipid droplet localized protein
    NP_001379806.1
    • Confirmed by transcript evidence
    NP_872194.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      2127535..2130100
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001392486.1 → NP_001379806.1  Lipid droplet localized protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8IA58, Q9GZE9
      Conserved Domains (1) summary
      COG3268
      Location:4 → 421
      COG3268; Uncharacterized conserved protein, related to short-chain dehydrogenases [Function unknown]

    2. NM_182394.7 → NP_872194.2  Lipid droplet localized protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9GZE9
      Conserved Domains (1) summary
      COG3268
      Location:1 → 299
      COG3268; Uncharacterized conserved protein, related to short-chain dehydrogenases [Function unknown]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9GZE9.1

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