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    F52C6.3 Ubiquitin-like domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 186085, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F52C6.3
    Official Full Name
    Ubiquitin-like domain-containing protein
    Primary source
    WormBase:WBGene00018660
    Locus tag
    CELE_F52C6.3
    See related
    AllianceGenome:WB:WBGene00018660
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables identical protein binding activity. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F52C6.3 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003280.10 (1924759..1925720)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene BTB domain-containing protein Neighboring gene Ubiquitin-like domain-containing protein Neighboring gene Ubiquitin-like domain-containing protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Integrating interactome, phenome, and transcriptome mapping data for the C. elegans germline. Walhout AJ, et al. Curr Biol, 2002 Nov 19. PMID 12445390
    2. A combined binary interaction and phenotypic map of C. elegans cell polarity proteins. Koorman T, et al. Nat Cell Biol, 2016 Mar. PMID 26780296, Free PMC Article
    3. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article
    4. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
    5. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein tag activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin protein ligase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in modification-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Ubiquitin-like domain-containing protein
    NP_494127.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      1924759..1925720
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_061726.5 → NP_494127.2  Ubiquitin-like domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_494127.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O44820
      Conserved Domains (1) summary
      cl28922
      Location:103 → 173
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    Nucleotide Protein
    Heading Accession and Version

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