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    kbp-3 Kinetochore-binding protein 3 [ Caenorhabditis elegans ]

    Gene ID: 175097, updated on 9-Dec-2024

    Summary

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    Official Symbol
    kbp-3
    Official Full Name
    Kinetochore-binding protein 3
    Primary source
    WormBase:WBGene00009179
    Locus tag
    CELE_F26H11.1
    See related
    AllianceGenome:WB:WBGene00009179
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in cell division. Located in kinetochore. Part of Ndc80 complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See kbp-3 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003280.10 (14389236..14390078, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Histone-lysine N-methyltransferase mes-2 Neighboring gene Secreted protein Neighboring gene Bromo domain-containing protein;Bromodomain-containing protein;DDT domain-containing protein;Nucleosome-remodeling factor subunit NURF301;Nucleosome-remodeling factor subunit NURF301-like Neighboring gene ncRNA Neighboring gene ULP_PROTEASE domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cheeseman IM, et al. Cell, 2006 Dec 1. PMID 17129783
    2. Crosstalk between microtubule attachment complexes ensures accurate chromosome segregation. Cheerambathur DK, et al. Science, 2013 Dec 6. PMID 24231804, Free PMC Article
    3. Kinetochores: if you build it, they will come. DeLuca JG, et al. Curr Biol, 2004 Nov 9. PMID 15530383
    4. A new mechanism controlling kinetochore-microtubule interactions revealed by comparison of two dynein-targeting components: SPDL-1 and the Rod/Zwilch/Zw10 complex. Gassmann R, et al. Genes Dev, 2008 Sep 1. PMID 18765790, Free PMC Article
    5. Chromatin and RNAi factors protect the C. elegans germline against repetitive sequences. Robert VJ, et al. Genes Dev, 2005 Apr 1. PMID 15774721, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of Ndc80 complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in kinetochore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in kinetochore IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Kinetochore-binding protein 3
    NP_496993.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      14389236..14390078 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064592.7 → NP_496993.1  Kinetochore-binding protein 3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496993.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O45406
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O45406.3

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