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    sws-1 SWIM-type domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 189734, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sws-1
    Official Full Name
    SWIM-type domain-containing protein
    Primary source
    WormBase:WBGene00012698
    Locus tag
    CELE_Y39B6A.40
    See related
    AllianceGenome:WB:WBGene00012698
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Human ortholog(s) of this gene implicated in 46 XX gonadal dysgenesis and spermatogenic failure 71. Orthologous to human ZSWIM7 (zinc finger SWIM-type containing 7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See sws-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (18979319..18981479, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Small ribosomal subunit protein mS35 mitochondrial conserved domain-containing protein Neighboring gene REPS (RalBP1-associated Eps domain-containing protein) homolog Neighboring gene Structural protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CRISPR Technology Reveals RAD(51)-ical Mechanisms of Repair in Roundworms: An Educational Primer for Use with "Promotion of Homologous Recombination by SWS-1 in Complex with RAD-51 Paralogs in Caenorhabditis elegans". Turcotte CA, et al. Genetics, 2016 Nov. PMID 28114101, Free PMC Article
    2. Promotion of Homologous Recombination by SWS-1 in Complex with RAD-51 Paralogs in Caenorhabditis elegans. McClendon TB, et al. Genetics, 2016 May. PMID 26936927, Free PMC Article
    3. Evolutionary and functional analysis of the invariant SWIM domain in the conserved Shu2/SWS1 protein family from Saccharomyces cerevisiae to Homo sapiens. Godin SK, et al. Genetics, 2015 Apr. PMID 25659377, Free PMC Article
    4. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in double-strand break repair via homologous recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Shu complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SWIM-type domain-containing protein
    NP_001300234.1
    • Confirmed by transcript evidence
    NP_001300235.1
    • Confirmed by transcript evidence
    NP_001380187.1
    • Confirmed by transcript evidence
    NP_741657.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      18979319..18981479 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001313305.2 → NP_001300234.1  SWIM-type domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AY91

    2. NM_171567.4 → NP_741657.2  SWIM-type domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741657.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MYM5

    3. NM_001392693.1 → NP_001380187.1  SWIM-type domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AV98

    4. NM_001313306.1 → NP_001300235.1  SWIM-type domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AT01
    Nucleotide Protein
    Heading Accession and Version

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