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    F45H10.2 Cytochrome b-c1 complex subunit 8 [ Caenorhabditis elegans ]

    Gene ID: 174992, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F45H10.2
    Official Full Name
    Cytochrome b-c1 complex subunit 8
    Primary source
    WormBase:WBGene00009739
    Locus tag
    CELE_F45H10.2
    See related
    AllianceGenome:WB:WBGene00009739
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Predicted to be located in mitochondrial inner membrane. Predicted to be part of respiratory chain complex III. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 4. Orthologous to human UQCRQ (ubiquinol-cytochrome c reductase complex III subunit VII). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F45H10.2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003280.10 (13491888..13493048, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene CPG4 domain-containing protein Neighboring gene Aldehyde dehydrogenase domain-containing protein Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 Neighboring gene MARVEL domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. β-Integrin de-phosphorylation by the Density-Enhanced Phosphatase DEP-1 attenuates EGFR signaling in C. elegans. Walser M, et al. PLoS Genet, 2017 Jan. PMID 28135265, Free PMC Article
    2. CCAR-1 works together with the U2AF large subunit UAF-1 to regulate alternative splicing. Lugano DI, et al. RNA Biol, 2024 Jan. PMID 38126797, Free PMC Article
    3. Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling. Artan M, et al. J Biol Chem, 2021 Sep. PMID 34416233, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitochondrial electron transport, ubiquinol to cytochrome c IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of respiratory chain complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of respiratory chain complex III IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of respiratory chain complex III IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cytochrome b-c1 complex subunit 8
    NP_496838.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      13491888..13493048 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064437.7 → NP_496838.1  Cytochrome b-c1 complex subunit 8 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496838.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45525
      Conserved Domains (1) summary
      pfam02939
      Location:11 → 87
      UcrQ; UcrQ family
    Nucleotide Protein
    Heading Accession and Version

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