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    ugt-25 UDP-glucuronosyltransferase [ Caenorhabditis elegans ]

    Gene ID: 172087, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ugt-25
    Official Full Name
    UDP-glucuronosyltransferase
    Primary source
    WormBase:WBGene00015692
    Locus tag
    CELE_C10H11.3
    See related
    AllianceGenome:WB:WBGene00015692
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Orthologous to several human genes including UGT2A3 (UDP glucuronosyltransferase family 2 member A3); UGT2B15 (UDP glucuronosyltransferase family 2 member B15); and UGT2B17 (UDP glucuronosyltransferase family 2 member B17). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ugt-25 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (4731606..4735276)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene UDP-glucuronosyltransferase Neighboring gene glucuronosyltransferase Neighboring gene Target of rapamycin complex subunit lst8 Neighboring gene Rho-associated protein kinase let-502 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Adaptive and specialised transcriptional responses to xenobiotic stress in Caenorhabditis elegans are regulated by nuclear hormone receptors. Jones LM, et al. PLoS One, 2013. PMID 23922869, Free PMC Article
    2. UDP-glycosyltransferase family in Haemonchus contortus: Phylogenetic analysis, constitutive expression, sex-differences and resistance-related differences. Matoušková P, et al. Int J Parasitol Drugs Drug Resist, 2018 Dec. PMID 30293057, Free PMC Article
    3. Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes. Suriyalaksh M, et al. iScience, 2022 Jan 21. PMID 35036864, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables UDP-glycosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables UDP-glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glucuronosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    UDP-glucuronosyltransferase
    NP_491438.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      4731606..4735276
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059037.6 → NP_491438.1  UDP-glucuronosyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491438.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      P91039
      Conserved Domains (2) summary
      PHA03392
      Location:1 → 477
      egt; ecdysteroid UDP-glucosyltransferase; Provisional
      pfam00201
      Location:29 → 530
      UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
    Nucleotide Protein
    Heading Accession and Version

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