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    lury-1 LURY-1-2 [ Caenorhabditis elegans ]

    Gene ID: 190703, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lury-1
    Official Full Name
    LURY-1-2
    Primary source
    WormBase:WBGene00013548
    Locus tag
    CELE_Y75B8A.11
    See related
    AllianceGenome:WB:WBGene00013548
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables neuropeptide receptor binding activity. Involved in several processes, including determination of adult lifespan; negative regulation of feeding behavior; and positive regulation of egg-laying behavior. Predicted to be located in extracellular region. Is expressed in M1 neuron; M2L; M2R; and coelomocyte. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See lury-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    4
    Sequence:
    Chromosome: III; NC_003281.10 (12186411..12190116)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene ARC105/Med15 mediator subunit C-terminal domain-containing protein Neighboring gene Putative polypeptide N-acetylgalactosaminyltransferase 11 Neighboring gene RING-type domain-containing protein Neighboring gene ncRNA Neighboring gene BBSome complex member bbs-7 Neighboring gene Secreted protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Neuropeptide signalling shapes feeding and reproductive behaviours in male Caenorhabditis elegans. Gadenne MJ, et al. Life Sci Alliance, 2022 Oct. PMID 35738805, Free PMC Article
    2. Luqin-like RYamide peptides regulate food-evoked responses in C. elegans. Ohno H, et al. Elife, 2017 Aug 29. PMID 28847365, Free PMC Article
    3. Evolution and Comparative Physiology of Luqin-Type Neuropeptide Signaling. Yañez-Guerra LA, et al. Front Neurosci, 2020. PMID 32132900, Free PMC Article
    4. An hourglass circuit motif transforms a motor program via subcellularly localized muscle calcium signaling and contraction. Sando SR, et al. Elife, 2021 Jul 2. PMID 34212858, Free PMC Article
    5. The neuropeptidergic connectome of C. elegans. Ripoll-Sánchez L, et al. Neuron, 2023 Nov 15. PMID 37935195, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables neuropeptide receptor binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in determination of adult lifespan IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of feeding behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of locomotion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in neuropeptide signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of egg-laying behavior IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    LURY-1-2
    NP_001255160.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      12186411..12190116
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268231.2 → NP_001255160.1  LURY-1-2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255160.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9XW71

    RNA

    1. NR_052792.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XW71.2

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