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    F39C12.1 GATOR2 complex protein MIO zinc-ribbon like domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180759, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F39C12.1
    Official Full Name
    GATOR2 complex protein MIO zinc-ribbon like domain-containing protein
    Primary source
    WormBase:WBGene00018193
    Locus tag
    CELE_F39C12.1
    See related
    AllianceGenome:WB:WBGene00018193
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in cellular response to amino acid starvation and positive regulation of TORC1 signaling. Predicted to be active in cytoplasm. Orthologous to human MIOS (meiosis regulator for oocyte development). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F39C12.1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    29
    Sequence:
    Chromosome: X; NC_003284.9 (4834868..4853195, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene CCDC22 N-terminal domain-containing protein Neighboring gene EGF-like domain-containing protein Neighboring gene Adducin-related protein 1;Class II aldolase/adducin N-terminal domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. In Vivo Interaction Proteomics in Caenorhabditis elegans Embryos Provides New Insights into P Granule Dynamics. Chen JX, et al. Mol Cell Proteomics, 2016 May. PMID 26912668, Free PMC Article
    2. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article
    3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in cellular response to amino acid starvation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of TORC1 signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    GATOR2 complex protein MIO zinc-ribbon like domain-containing protein
    NP_001360031.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      4834868..4853195 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001373285.2 → NP_001360031.1  GATOR2 complex protein MIO zinc-ribbon like domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      O61201
      Conserved Domains (3) summary
      PTZ00449
      Location:3020 → 3470
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      COG3147
      Location:2883 → 2991
      DedD; Cell division protein DedD (periplasmic protein involved in septation) [Cell cycle control, cell division, chromosome partitioning]
      cd16691
      Location:4997 → 5060
      mRING-H2-C3H3C2_Mio; Modified RING finger, H2 subclass (C3H3C2-type), found in WD repeat-containing protein mio and simialr proteins
    Nucleotide Protein
    Heading Accession and Version

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